Cefazid 1 gm/vial (IM/IV Injection)

1 gm vial: ৳ 240.00

Medicine Details

Category Details
Generic Ceftazidime pentahydrate
Company Renata limited
Also available as
Cefazid 250 mg injection Cefazid 500 mg injection

Indications

  • Lower Respiratory Tract Infections
  • Skin and Skin Structure Infections
  • Urinary Tract Infections
  • Bacterial Septicemia
  • Bone and Joint Infections
  • Gynecologic Infections
  • Intraabdominal Infections
  • Central Nervous System Infections

Pharmacology

Ceftazidime is a broad-spectrum antibiotic for parenteral administration, bactericidal in action, inhibits cell-wall synthesis, susceptible to a wide range of gram-negative organisms, stable to clinically important beta-lactamases, active against gram-positive organisms.

Dosage

  • Usual adult dosage is 1 gram intravenously or intramuscularly every 8 to 12 hours
  • Dosage and route determined by susceptibility of causative organisms, severity of infection, patient's condition, and renal function
  • Dosage varies for adults, elderly, cystic fibrosis patients, infants, children, neonates

Administration

Can be given intravenously or by deep IM injection, should be reconstituted with sterile water for injection

Contraindications

  • Contraindicated in patients hypersensitive to Ceftazidime or cephalosporin group of antibiotics

Side Effects

  • Local reactions following IV injection
  • Allergic and gastrointestinal reactions
  • Hypersensitivity reactions
  • Gastrointestinal symptoms
  • Central nervous system reactions

Pregnancy & Lactation

  • Limited data for pregnancy, use only if clearly needed
  • Excreted in human milk in low concentrations, safety in nursing infants not established

Precautions & Warnings

  • Dosage should be reduced in renal insufficiency
  • Prescribed with caution in individuals with history of gastrointestinal disease

Use in Special Populations

  • Adjusted dosage for impaired renal function
  • Use in peritoneal dialysis and continuous ambulatory peritoneal dialysis
  • No adjustment in dosage for patients with hepatic dysfunction

Overdose Effects

Reactions include seizure activity, encephalopathy, neuromuscular excitability, and coma, supportive treatment is necessary.

Therapeutic Class

Third generation Cephalosporins

Reconstitution

Specific amounts of sterile water for injection for different doses and routes of administration

Storage Conditions

Store below 25°C, protected from light and moisture, reconstituted solutions stable for up to 24 hours if stored between 2°C-8°C

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