Ceftazim 500 mg/vial (IM/IV Injection)

500 mg vial: ৳ 130.00

Medicine Details

Category Details
Generic Ceftazidime pentahydrate
Company Aristopharma ltd
Also available as
Ceftazim 250 mg injection Ceftazim 1 gm injection

Title

  • Ceftazim Injection

Categories

  • Medicine
  • Antibiotic
  • Pharmaceutical

Description

  • Ceftazim Injection is indicated for the treatment of patients with infections caused by susceptible strains of various organisms in different diseases such as Lower Respiratory Tract Infections, Skin and Skin Structure Infections, Urinary Tract Infections, Bacterial Septicemia, Bone and Joint Infections, Gynecologic Infections, Intraabdominal Infections, Central Nervous System Infections.

Color Options

  • Clear solution

Dosage Form

  • Injection

Dosage Strength

  • 250mg
  • 500mg
  • 1g

Route of Administration

  • Intravenous
  • Intramuscular

Usual Adult Dosage

  • 1 gram administered intravenously or intramuscularly every 8 to 12 hours

Dosage Range for Adults

  • 1 to 6 gm per day 8 or 12 hourly (IM/IV)

Dosage for Urinary Tract Infections

  • 500 mg or 1 gm 12 hourly

Dosage for Severe Infections

  • 2 gm 8 or 12 hourly

Dosage for Cystic Fibrosis

  • 100 to 150 mg/kg/day as three divided doses for fibrocystic adults with normal renal function

Dosage for Infants and Children

  • 30 to 100 mg/kg/day for children aged over two months

Dosage for Neonates and Children up to 2 months of age

  • 25 to 60 mg/kg/day as two divided doses

Administration Method

  • Intravenous
  • Intramuscular

Contraindications

  • Hypersensitivity to Ceftazim or cephalosporin group of antibiotics

Side Effects

  • Local reactions following IV injection
  • Allergic and gastrointestinal reactions
  • Hypersensitivity reactions like pruritus, rash, fever
  • Gastrointestinal symptoms like diarrhea, nausea, vomiting, abdominal pain
  • Central nervous system reactions like headache, dizziness, paresthesia

Pregnancy

  • Should be used during pregnancy only if clearly needed

Lactation

  • Decision should be made whether to discontinue nursing or the drug, taking into account the importance of the drug to the mother

Precautions

  • Reduce total daily dosage in patients with renal insufficiency
  • Prescribed with caution in individuals with a history of gastrointestinal disease, particularly colitis

Special Populations

  • Impaired Renal Function
  • Impaired Hepatic Function

Therapeutic Class

  • Third generation Cephalosporins

Storage Conditions

  • Store below 25°C, protected from light and moisture

Reconstitution

  • Amount of WFI to be added: 250 mg IM in 1.5 ml, 250 mg IV in 5 ml, 500 mg IM in 1.5 ml, 500 mg IV in 5 ml, 1 g IM in 3 ml, 1 g IV in 10 ml

Pharmacology

  • Ceftazidime is bactericidal and inhibits enzymes responsible for cell-wall synthesis
  • Active against gram-negative and gram-positive organisms
  • Stable to most clinically important beta-lactamases

Overdose Effects

  • Seizure activity, encephalopathy, neuromuscular excitability, coma in patients with renal failure

Drug Classes

  • Antibiotic
  • Beta-lactam antibiotic
  • Cephalosporin

Storage Stability

  • Reconstituted solutions are stable for up to 24 h if stored between 2°C-8°C

Related Brands