Ceftazim 1 gm/vial (IM/IV Injection)

1 gm vial: ৳ 240.00

Medicine Details

Category	Details
Generic	Ceftazidime pentahydrate
Company	Aristopharma ltd
Also available as	Ceftazim 250 mg injection Ceftazim 500 mg injection

Indications

Lower Respiratory Tract Infections
Skin and Skin Structure Infections
Urinary Tract Infections
Bacterial Septicemia
Bone and Joint Infections
Gynecologic Infections
Intraabdominal Infections
Central Nervous System Infections

Pharmacology

Ceftazidime is a semisynthetic, broad-spectrum, beta-lactam antibiotic for parenteral administration. It is bactericidal in action exerting its effect by inhibition of enzymes responsible for cell-wall synthesis.

Dosage

The usual adult dosage is 1 gram administered intravenously or intramuscularly every 8 to 12 hours. Dosage and route should be determined by the susceptibility of the causative organisms, the severity of infection, and the condition and renal function of the patient.

Administration

Ceftazidime may be given intravenously or by deep IM injection into a large muscle mass such as the upper outer quadrant of the gluteus maximus or lateral proof of the thigh.

Contraindications

Ceftazidime is contraindicated in patients who have shown hypersensitivity to Ceftazidime or the cephalosporin group of antibiotics.

Side Effects

Local reactions following IV injection
Allergic and gastrointestinal reactions
Hypersensitivity reactions
Gastrointestinal symptoms
Central nervous system reactions

Pregnancy & Lactation

No adequate and well-controlled studies in pregnant women
Ceftazidime is excreted in human milk in low concentrations

Precautions & Warnings

The total daily dosage should be reduced when Ceftazim is administered to patients with renal insufficiency.

Use in Special Populations

Impaired Renal Function
Dosage in peritoneal dialysis
Impaired Hepatic Function

Overdose Effects

Reactions have included seizure activity, encephalopathy, asterixis, neuromuscular excitability, and coma. Patients who receive an acute overdosage should be carefully observed and given supportive treatment.

Therapeutic Class

Third generation Cephalosporins

Reconstitution

Single-dose vial Administration Amount of WFI to be added: 250 mg IM in 1.5 ml, 250 mg IV in 5 ml, 500 mg IM in 1.5 ml, 500 mg IV in 5 ml and 1 g IM in 3 ml, 1 g IV in 10 ml.

Storage Conditions

Store below 25°C, protected from light and moisture. Reconstituted solutions are stable for up to 24 h if stored between 2°C-8°C.