Cefzon 250 mg/vial (IM/IV Injection)

250 mg vial: ৳ 80.00

Medicine Details

Category Details
Generic Ceftazidime pentahydrate
Company Navana pharmaceuticals ltd
Also available as
Cefzon 500 mg injection Cefzon 1 gm injection

Indications

  • Lower Respiratory Tract Infections
  • Skin and Skin Structure Infections
  • Urinary Tract Infections
  • Bacterial Septicemia
  • Bone and Joint Infections
  • Gynecologic Infections
  • Intraabdominal Infections
  • Central Nervous System Infections

Pharmacology

  • Semisynthetic
  • Broad-spectrum
  • Beta-lactam antibiotic
  • Bactericidal
  • Inhibition of enzymes
  • Susceptible to gram-negative organisms
  • Active against gram-positive organisms
  • Stable to beta-lactamases

Dosage

  • Usual adult dosage is 1 gram every 8 to 12 hours
  • Route determined by susceptibility of causative organisms
  • Variety of dosage ranges for different infection types
  • Dosage adjustments for elderly, infants, and children

Administration

  • Intravenous or deep IM injection
  • Reconstitution with Sterile Water for Injection
  • Avoidance of intra-arterial administration

Contraindications

  • Hypersensitivity to Ceftazidime or cephalosporin antibiotics

Side Effects

  • Local reactions following IV injection
  • Allergic and gastrointestinal reactions
  • Hypersensitivity reactions like pruritus, rash, and fever
  • Gastrointestinal symptoms like diarrhea, nausea, and vomiting
  • Central nervous system reactions like headache and dizziness

Pregnancy & Lactation

  • Limited data for use during pregnancy
  • Excretion in low concentrations in human milk
  • Consideration for discontinuation of nursing

Precautions & Warnings

  • Reduced dosage for patients with renal insufficiency
  • Caution in patients with a history of gastrointestinal disease

Use in Special Populations

  • Dosage reduction in impaired renal function
  • Use in peritoneal dialysis and continuous ambulatory peritoneal dialysis
  • No adjustment in dosage for impaired hepatic function

Overdose Effects

  • Occurrence in patients with renal failure
  • Reactions may include seizure activity, encephalopathy, and coma
  • Careful observation and supportive treatment for acute overdosage

Therapeutic Class

Third generation Cephalosporins

Reconstitution

Instructions for reconstitution of single-dose vial administration

Storage Conditions

  • Storage below 25°C
  • Protection from light and moisture
  • Stability of reconstituted solutions for up to 24 hours if stored between 2°C-8°C

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