Amdocal Plus 5 mg+25 mg (Tablet)

Unit Price: ৳ 6.50 (3 x 10: ৳ 195.00)
Strip Price: ৳ 65.00

Medicine Details

Category Details
Generic Amlodipine besilate atenolol
Company Beximco pharmaceuticals ltd
Also available as
Amdocal plus 5 mg tablet

Indications

  • Patients with essential hypertension
  • Patients with angina pectoris & hypertension as co-existing diseases
  • In post Ml patients
  • In patients with refractory angina pectoris where nitrate therapy has failed.

Pharmacology

  • Dihydropyridine calcium antagonist
  • Peripheral vasodilator
  • Cardioselective beta-blocker
  • Reduction in peripheral vascular resistance
  • Reduction in blood pressure
  • Reduction in myocardial oxygen demand

Dosage and administration

  • Recommended dosage: Amlodipine and Atenolol 5/25 mg tablet once daily
  • Dosage may be increased to 5/25 mg two tablets daily or as advised by physicians
  • Dosage should be individualized.

Interaction

  • Ampicillin may reduce Atenolol levels
  • Beta-blockers may decrease tissue sensitivity to insulin and inhibit insulin secretion
  • Atenolol reduces the clearance of disopyramide by 20%

Contraindications

  • Hypersensitivity to either component
  • Sinus bradycardia
  • Second and higher degrees of heart block
  • Cardiogenic shock
  • Hypotension
  • Congestive heart failure
  • Poor left ventricular function

Side effects

  • Fatigue
  • Headache
  • Edema
  • Nausea
  • Drowsiness
  • Anxiety
  • Depression

Pregnancy and lactation

  • Use during pregnancy only if expected benefit outweighs potential fetal risk
  • Not recommended for nursing mothers
  • Breast-feeding should be stopped if use is considered necessary

Precautions and warnings

  • Use with caution in patients with airway obstruction
  • Caution in patients with renal impairment
  • Caution in patients with severe liver damage
  • Patients should be warned against stopping the drug suddenly

Overdose effects

  • Hypotension
  • Congestive cardiac failure
  • Unabsorbed drugs may be removed by gastric lavage or activated charcoal
  • Symptomatic treatment is suggested

Therapeutic class

  • Combined antihypertensive preparations

Storage conditions

  • Keep below 30°C temperature
  • Keep away from light & moisture
  • Keep out of the reach of children

Related Brands