Maxidim 250 mg/vial (IM/IV Injection)

250 mg vial: ৳ 85.00

Medicine Details

Category	Details
Generic	Ceftazidime pentahydrate
Company	Beximco pharmaceuticals ltd
Also available as	Maxidim 500 mg injection Maxidim 1 gm injection

Indications

Lower Respiratory Tract Infections
Skin and Skin Structure Infections
Urinary Tract Infections
Bacterial Septicemia
Bone and Joint Infections
Gynecologic Infections
Intraabdominal Infections
Central Nervous System Infections

Pharmacology

Ceftazidime is a semisynthetic, broad-spectrum, beta-lactam antibiotic for parenteral administration.

Dosage

Usual adult dosage is 1 gram administered intravenously or intramuscularly every 8 to 12 hours
Dosage and route determined by susceptibility of causative organisms, severity of infection, and patient's condition and renal function

Administration

Ceftazidime may be given intravenously or by deep IM injection

Contraindications

Contraindicated in patients with hypersensitivity to Ceftazidime or the cephalosporin group of antibiotics

Side Effects

Local reactions following IV injection
Allergic and gastrointestinal reactions
Hypersensitivity reactions such as pruritus, rash, and fever
Gastrointestinal symptoms including diarrhea, nausea, vomiting, and abdominal pain
Central nervous system reactions like headache, dizziness, and paresthesia

Pregnancy & Lactation

No adequate and well-controlled studies in pregnant women
Drug excreted in human milk in low concentrations

Precautions & Warnings

Total daily dosage reduced when administered to patients with renal insufficiency
Prescribed with caution in individuals with a history of gastrointestinal disease, particularly colitis

Use in Special Populations

Impaired Renal Function
Dosage in peritoneal dialysis
Impaired Hepatic Function

Overdose Effects

Overdosage occurred in patients with renal failure, including seizure activity, encephalopathy, asterixis, neuromuscular excitability, and coma

Therapeutic Class

Third generation Cephalosporins

Reconstitution

Single-dose vial Administration Amount of WFI to be added: 250 mg IM in 1.5 ml, 250 mg IV in 5 ml, 500 mg IM in 1.5 ml, 500 mg IV in 5 ml and 1 g IM in 3 ml, 1 g IV in 10 ml

Storage Conditions

Store below 25°C, protected from light and moisture