Maxidim 500 mg/vial (IM/IV Injection)

500 mg vial: ৳ 130.00

Medicine Details

Category Details
Generic Ceftazidime pentahydrate
Company Beximco pharmaceuticals ltd
Also available as
Maxidim 250 mg injection Maxidim 1 gm injection

Title

  • Maxidim Injection

Categories

  • Medicine
  • Pharmaceutical

Description

  • Ceftazidime is a broad-spectrum antibiotic for treating various infections caused by susceptible organisms.

Indications

  • Lower Respiratory Tract Infections
  • Skin and Skin Structure Infections
  • Urinary Tract Infections
  • Bacterial Septicemia
  • Bone and Joint Infections
  • Gynecologic Infections
  • Intraabdominal Infections
  • Central Nervous System Infections

Pharmacology

  • Bactericidal action
  • Inhibition of cell-wall synthesis
  • Susceptibility to gram-negative organisms
  • Activity against gram-positive organisms
  • Stability to beta-lactamases

Dosage

  • 1 gram dosage for adults every 8 to 12 hours
  • Dosage determination based on susceptibility, infection severity, and patient condition and renal function

Administration

  • Intravenous or deep IM injection
  • Reconstitution with Sterile Water for Injection

Contraindications

  • Hypersensitivity to Ceftazidime or cephalosporin antibiotics

Side Effects

  • Local reactions following IV injection
  • Allergic and gastrointestinal reactions
  • Pruritus, rash, fever, angioedema, anaphylaxis
  • Gastrointestinal symptoms like diarrhea, nausea, vomiting, abdominal pain
  • Central nervous system reactions including headache, dizziness

Pregnancy & Lactation

  • Use during pregnancy only if clearly needed
  • Excretion in human milk in low concentrations
  • Consideration of drug importance to the mother in decision-making

Precautions & Warnings

  • Caution in patients with renal insufficiency
  • Prescription caution in individuals with history of gastrointestinal disease

Use in Special Populations

  • Dosage reduction in renal insufficiency
  • Use in peritoneal dialysis and continuous ambulatory peritoneal dialysis (CAPD)
  • No adjustment in dosage for patients with hepatic dysfunction

Overdose Effects

  • Seizure activity
  • Encephalopathy
  • Asterixis
  • Neuromuscular excitability
  • Coma
  • Supportive treatment for acute overdosage

Therapeutic Class

  • Third generation Cephalosporins

Reconstitution

  • Specific amounts of WFI for different doses and administration types

Storage Conditions

  • Storage below 25°C
  • Protection from light and moisture
  • Stability of reconstituted solutions for up to 24 hours if stored between 2°C-8°C

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