Tazid 500 mg/vial (IM/IV Injection)
500 mg vial: ৳ 130.39
Medicine Details
| Category | Details |
|---|---|
| Generic | Ceftazidime pentahydrate |
| Company | Square pharmaceuticals plc |
| Also available as |
Product Title
- Tazid Injection
Categories
- Antibiotics
- Infection Treatment
- Parenteral Medication
Description
- Broad-spectrum antibiotic
- Indicated for lower respiratory tract infections
- Effective against gram-negative organisms
- Usable for skin and skin structure infections
- Suitable for urinary tract infections
- Can be used for bacterial septicemia
- Effective for bone and joint infections
- Applicable for gynecologic infections
- Suitable for intraabdominal infections
- Effective for central nervous system infections
- Semisynthetic beta-lactam antibiotic
- Bactericidal in action
- Inhibits cell-wall synthesis
- Stable to clinically important beta-lactamases
- Contraindicated in patients with hypersensitivity to ceftazidime
- Common side effects include local reactions, allergic and gastrointestinal reactions
- Pregnancy use should be considered only if clearly needed
- May be excreted in low concentrations in human milk
- Dosage should be reduced in patients with renal insufficiency
- Recommended caution in individuals with a history of gastrointestinal disease
- Dose adjustment required for patients with impaired renal function
- Usable in peritoneal dialysis and continuous ambulatory peritoneal dialysis (CAPD)
- No dosage adjustment required for patients with hepatic dysfunction
- Overdose may lead to seizure activity, encephalopathy, and coma
- Belongs to the therapeutic class of third generation cephalosporins
- Requires reconstitution before administration
- Store below 25°C, protected from light and moisture
Dosage
- 1 gram administered intravenously or intramuscularly every 8 to 12 hours for adults
- Dosage depends on the susceptibility of causative organisms and severity of infection
- Reduced clearance of ceftazidime in acutely ill elderly patients
Mode of Action
- Exerts effect by inhibiting enzymes responsible for cell-wall synthesis
- Highly stable to most clinically important beta-lactamases
Administration
- May be given intravenously or by deep IM injection
Contraindications
- Hypersensitivity to ceftazidime or cephalosporin group of antibiotics
Side Effects
- Local reactions following IV injection
- Allergic and gastrointestinal reactions
- Hypersensitivity reactions like pruritus, rash, and fever
Pregnancy & Lactation
- No adequate and well-controlled studies in pregnant women
- Considered during pregnancy only if clearly needed
- Excreted in human milk in low concentrations
Precautions & Warnings
- Total daily dosage should be reduced in patients with renal insufficiency
- Prescribed with caution in individuals with a history of gastrointestinal disease
Use in Special Populations
- Dosage adjustment required for patients with impaired renal function
- Usable in peritoneal dialysis and CAPD
Overdose Effects
- Seizure activity, encephalopathy, and coma
Therapeutic Class
- Third generation Cephalosporins
Reconstitution
- Requires reconstitution with Sterile Water for Injection before administration
Storage Conditions
- Store below 25°C
- Protected from light and moisture
- Reconstituted solutions are stable for up to 24 hours if stored between 2°C-8°C