Tazid 500 mg/vial (IM/IV Injection)

500 mg vial: ৳ 130.39

Medicine Details

Category Details
Generic Ceftazidime pentahydrate
Company Square pharmaceuticals plc
Also available as
Tazid 250 mg injection Tazid 1 gm injection

Product Title

  • Tazid Injection

Categories

  • Antibiotics
  • Infection Treatment
  • Parenteral Medication

Description

  • Broad-spectrum antibiotic
  • Indicated for lower respiratory tract infections
  • Effective against gram-negative organisms
  • Usable for skin and skin structure infections
  • Suitable for urinary tract infections
  • Can be used for bacterial septicemia
  • Effective for bone and joint infections
  • Applicable for gynecologic infections
  • Suitable for intraabdominal infections
  • Effective for central nervous system infections
  • Semisynthetic beta-lactam antibiotic
  • Bactericidal in action
  • Inhibits cell-wall synthesis
  • Stable to clinically important beta-lactamases
  • Contraindicated in patients with hypersensitivity to ceftazidime
  • Common side effects include local reactions, allergic and gastrointestinal reactions
  • Pregnancy use should be considered only if clearly needed
  • May be excreted in low concentrations in human milk
  • Dosage should be reduced in patients with renal insufficiency
  • Recommended caution in individuals with a history of gastrointestinal disease
  • Dose adjustment required for patients with impaired renal function
  • Usable in peritoneal dialysis and continuous ambulatory peritoneal dialysis (CAPD)
  • No dosage adjustment required for patients with hepatic dysfunction
  • Overdose may lead to seizure activity, encephalopathy, and coma
  • Belongs to the therapeutic class of third generation cephalosporins
  • Requires reconstitution before administration
  • Store below 25°C, protected from light and moisture

Dosage

  • 1 gram administered intravenously or intramuscularly every 8 to 12 hours for adults
  • Dosage depends on the susceptibility of causative organisms and severity of infection
  • Reduced clearance of ceftazidime in acutely ill elderly patients

Mode of Action

  • Exerts effect by inhibiting enzymes responsible for cell-wall synthesis
  • Highly stable to most clinically important beta-lactamases

Administration

  • May be given intravenously or by deep IM injection

Contraindications

  • Hypersensitivity to ceftazidime or cephalosporin group of antibiotics

Side Effects

  • Local reactions following IV injection
  • Allergic and gastrointestinal reactions
  • Hypersensitivity reactions like pruritus, rash, and fever

Pregnancy & Lactation

  • No adequate and well-controlled studies in pregnant women
  • Considered during pregnancy only if clearly needed
  • Excreted in human milk in low concentrations

Precautions & Warnings

  • Total daily dosage should be reduced in patients with renal insufficiency
  • Prescribed with caution in individuals with a history of gastrointestinal disease

Use in Special Populations

  • Dosage adjustment required for patients with impaired renal function
  • Usable in peritoneal dialysis and CAPD

Overdose Effects

  • Seizure activity, encephalopathy, and coma

Therapeutic Class

  • Third generation Cephalosporins

Reconstitution

  • Requires reconstitution with Sterile Water for Injection before administration

Storage Conditions

  • Store below 25°C
  • Protected from light and moisture
  • Reconstituted solutions are stable for up to 24 hours if stored between 2°C-8°C

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