Tizime 500 mg/vial (IM/IV Injection)

500 mg vial: ৳ 115.00

Medicine Details

Category	Details
Generic	Ceftazidime pentahydrate
Company	Globe pharmaceuticals ltd
Also available as	Tizime 250 mg injection Tizime 1 gm injection

Title

Tizime Injection

Categories

Medicine
Pharmaceutical

Indications

Lower Respiratory Tract Infections
Skin and Skin Structure Infections
Urinary Tract Infections
Bacterial Septicemia
Bone and Joint Infections
Gynecologic Infections
Intraabdominal Infections
Central Nervous System Infections

Pharmacology

Bactericidal action, inhibition of cell-wall synthesis, susceptibility to gram-negative and gram-positive organisms, stability to beta-lactamases

Dosage

1 gram administered intravenously or intramuscularly every 8 to 12 hours
Different dosages based on severity, sensitivity, type of infection, age, weight, renal function

Administration

Intravenous or deep IM injection into a large muscle mass
Reconstitution with Sterile Water for Injection

Contraindications

Hypersensitivity to Ceftazidime or cephalosporin antibiotics

Side Effects

Local reactions following IV injection
Allergic reactions
Gastrointestinal symptoms
Central nervous system reactions

Pregnancy & Lactation

Limited studies in pregnant women
Excretion in human milk
Safety not established for nursing infants

Precautions & Warnings

Reduce dosage in renal insufficiency
Prescribed with caution in individuals with history of gastrointestinal disease

Use in Special Populations

Dosage reduction in impaired renal function
Usage in peritoneal dialysis and CAPD
No adjustment in dosage required for hepatic dysfunction

Overdose Effects

Reactions include seizure activity, encephalopathy, neuromuscular excitability

Therapeutic Class

Third generation Cephalosporins

Reconstitution

Amount of WFI to be added for different administration types

Storage Conditions

Store below 25°C
Protected from light and moisture
Reconstituted solutions are stable for up to 24 hours if stored between 2°C-8°C

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