Trizidim 500 mg/vial (IM/IV Injection)
500 mg vial: ৳ 115.78
Medicine Details
| Category | Details |
|---|---|
| Generic | Ceftazidime pentahydrate |
| Company | Acme laboratories ltd |
| Also available as |
Title and Categories
- Trizidim Injection
- Third generation Cephalosporins
Indications
- Lower Respiratory Tract Infections
- Skin and Skin Structure Infections
- Urinary Tract Infections
- Bacterial Septicemia
- Bone and Joint Infections
- Gynecologic Infections
- Intraabdominal Infections
- Central Nervous System Infections
Pharmacology
- Bactericidal Action
- Inhibition of Cell-wall Synthesis
- Susceptibility to Gram-negative Organisms
- Activity Against Gram-positive Organisms
- Stability to Beta-lactamases
Dosage
- Usual Adult Dosage: 1 gram administered intravenously or intramuscularly every 8 to 12 hours
- Dosage Range for Adults: 1 to 6 gm per day 8 or 12 hourly (IM/IV)
- Dosage Range for Children: 30 to 100 mg/kg/day
- Dosage for Neonates and Children up to 2 months of age: 25 to 60 mg/kg/day
Administration
- Intravenous or Deep Intramuscular Injection
- Reconstitution with Sterile Water for Injection
Contraindications
- Hypersensitivity to Ceftazidime or Cephalosporins
Side Effects
- Local Reactions following IV Injection
- Allergic Reactions
- Gastrointestinal Reactions
- Central Nervous System Reactions
Pregnancy & Lactation
- Pregnancy: Use only if clearly needed
- Lactation: Decision should be made whether to discontinue nursing or drug
Precautions & Warnings
- Reduced dosage for patients with renal insufficiency
- Prescribed with caution in individuals with a history of gastrointestinal disease
Impaired Renal Function
- Dosage reduction for glomerular filtration rate <50 mL/min
- Initial loading dose of 1 gram
Overdose Effects
- Seizure Activity
- Encephalopathy
- Neuromuscular Excitability
- Coma
Reconstitution
- Amount of WFI to be added for IM and IV administration
Storage Conditions
- Storage below 25°C
- Reconstituted solutions stable for up to 24 hours if stored between 2°-8°C