Trizidim 500 mg/vial (IM/IV Injection)

500 mg vial: ৳ 115.78

Medicine Details

Category	Details
Generic	Ceftazidime pentahydrate
Company	Acme laboratories ltd
Also available as	Trizidim 250 mg injection Trizidim 1 gm injection

Title and Categories

Trizidim Injection
Third generation Cephalosporins

Indications

Lower Respiratory Tract Infections
Skin and Skin Structure Infections
Urinary Tract Infections
Bacterial Septicemia
Bone and Joint Infections
Gynecologic Infections
Intraabdominal Infections
Central Nervous System Infections

Pharmacology

Bactericidal Action
Inhibition of Cell-wall Synthesis
Susceptibility to Gram-negative Organisms
Activity Against Gram-positive Organisms
Stability to Beta-lactamases

Dosage

Usual Adult Dosage: 1 gram administered intravenously or intramuscularly every 8 to 12 hours
Dosage Range for Adults: 1 to 6 gm per day 8 or 12 hourly (IM/IV)
Dosage Range for Children: 30 to 100 mg/kg/day
Dosage for Neonates and Children up to 2 months of age: 25 to 60 mg/kg/day

Administration

Intravenous or Deep Intramuscular Injection
Reconstitution with Sterile Water for Injection

Contraindications

Hypersensitivity to Ceftazidime or Cephalosporins

Side Effects

Local Reactions following IV Injection
Allergic Reactions
Gastrointestinal Reactions
Central Nervous System Reactions

Pregnancy & Lactation

Pregnancy: Use only if clearly needed
Lactation: Decision should be made whether to discontinue nursing or drug

Precautions & Warnings

Reduced dosage for patients with renal insufficiency
Prescribed with caution in individuals with a history of gastrointestinal disease

Impaired Renal Function

Dosage reduction for glomerular filtration rate <50 mL/min
Initial loading dose of 1 gram

Overdose Effects

Seizure Activity
Encephalopathy
Neuromuscular Excitability
Coma

Reconstitution

Amount of WFI to be added for IM and IV administration

Storage Conditions

Storage below 25°C
Reconstituted solutions stable for up to 24 hours if stored between 2°-8°C

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