Trizidim 1 gm/vial (IM/IV Injection)

1 gm vial: ৳ 216.45

Medicine Details

Category Details
Generic Ceftazidime pentahydrate
Company Acme laboratories ltd
Also available as
Trizidim 250 mg injection Trizidim 500 mg injection

Title and Categories

  • Trizidim Injection
  • Third generation Cephalosporins
  • Medicine
  • Pharmaceuticals

Indications

  • Lower Respiratory Tract Infections
  • Skin and Skin Structure Infections
  • Urinary Tract Infections
  • Bacterial Septicemia
  • Bone and Joint Infections
  • Gynecologic Infections
  • Intraabdominal Infections
  • Central Nervous System Infections

Pharmacology

  • Bactericidal
  • Broad-spectrum
  • Beta-lactam antibiotic
  • Inhibition of cell-wall synthesis
  • Stable to most clinically important beta-lactamases

Dosage

  • Usual adult dosage 1 gram every 8 to 12 hours
  • Dosage determined by susceptibility of causative organisms
  • Dosage depending upon severity, sensitivity & type of infections and the age, weight & renal function of the patient
  • Different dosage for urinary tract infections, severe infections, elderly, cystic fibrosis, infants and children, neonates and children up to 2 months of age

Administration

  • Intravenous or deep IM injection
  • Reconstitution with Sterile Water for Injection
  • Intra-arterial administration should be avoided

Contraindications

  • Hypersensitivity to Ceftazidime or cephalosporin group of antibiotics

Side Effects

  • Local reactions following IV injection
  • Allergic reactions
  • Gastrointestinal symptoms
  • Central nervous system reactions

Pregnancy & Lactation

  • No adequate and well-controlled studies in pregnant women
  • Excretion in human milk in low concentrations

Precautions & Warnings

  • Reduced dosage for patients with renal insufficiency
  • Prescribed with caution in individuals with a history of gastrointestinal disease

Use in Special Populations

  • Dosage reduction in impaired renal function
  • Usage in peritoneal dialysis and continuous ambulatory peritoneal dialysis (CAPD)
  • No dosage adjustment required for patients with hepatic dysfunction

Overdose Effects

  • Occurred in patients with renal failure
  • Reactions including seizure activity, encephalopathy, neuromuscular excitability, and coma

Reconstitution

  • Amount of WFI to be added for IM and IV administration

Storage Conditions

  • Store below 25°C
  • Protected from light and moisture
  • Reconstituted solutions stable for up to 24 h if stored between 2°C-8°C

Related Brands