Trum 3 250 mg/vial (IM/IV Injection)
250 mg vial: ৳ 70.25
Medicine Details
| Category | Details |
|---|---|
| Generic | Ceftazidime pentahydrate |
| Company | Drug international ltd |
| Also available as |
Title
- Trum 3 Injection
Categories
- Antibiotics
- Cephalosporins
- Medication
- Pharmaceuticals
- Clinical Treatment
Description
- Broad-spectrum antibiotic
- Parenteral administration
- Bactericidal action
- Cell-wall synthesis inhibition
- Gram-negative organism susceptibility
- Resistance to gentamicin and aminoglycosides
- Activity against gram-positive organisms
- Beta-lactamase stability
- Contraindicated in hypersensitivity
- Common side effects: local reactions, allergic reactions, gastrointestinal reactions
- Hypersensitivity reactions: pruritus, rash, fever
- Rare hypersensitivity reactions: angioedema, anaphylaxis
- Gastrointestinal symptoms: diarrhea, nausea, vomiting, abdominal pain
- Central nervous system reactions: headache, dizziness, paresthesia
- Pregnancy caution
- Lactation caution
- Renal insufficiency dosage adjustment
- History of gastrointestinal disease caution
- Impaired renal function precautions
- Dosage adjustment in renal insufficiency
- Dosage in peritoneal dialysis
- No dosage adjustment for hepatic dysfunction
- Overdosage effects: seizure activity, encephalopathy, neuromuscular excitability, coma
- Third generation cephalosporins
- Storage temperature conditions
- Reconstitution guidelines
Indications
- Lower Respiratory Tract Infections
- Skin and Skin Structure Infections
- Urinary Tract Infections
- Bacterial Septicemia
- Bone and Joint Infections
- Gynecologic Infections
- Intraabdominal Infections
- Central Nervous System Infections
Pharmacology
- Inhibition of cell-wall synthesis
- Broad-spectrum action
- Gram-negative organism susceptibility
- Resistance to gentamicin and aminoglycosides
- Activity against gram-positive organisms
- Beta-lactamase stability
Dosage
- Adult dosage: 1 gram every 8 to 12 hours
- Dosage determined by susceptibility, infection severity, renal function
- Dosage range for adults: 1 to 6 gm per day
- Dosage reductions for elderly patients
- Dosage range for children: 30 to 100 mg/kg/day
- Dosage for neonates and children up to 2 months: 25 to 60 mg/kg/day
Administration
- Options: intravenous or deep IM injection
- Avoid intra-arterial administration
- Reconstitution with Sterile Water for Injection
Contraindications
- Hypersensitivity to Ceftazidime or cephalosporins
Side effects
- Local reactions following IV injection
- Allergic and gastrointestinal reactions
- Hypersensitivity reactions: pruritus, rash, fever
- Rare hypersensitivity reactions: angioedema, anaphylaxis
- Gastrointestinal symptoms: diarrhea, nausea, vomiting, abdominal pain
- Central nervous system reactions: headache, dizziness, paresthesia
Pregnancy lactation
- Pregnancy: Use only if clearly needed
- Lactation: Caution due to low excretion in human milk
Precautions warnings
- Dosage reduction in renal insufficiency
- Caution in individuals with gastrointestinal disease
- Caution in impaired renal and hepatic function
Special populations
- Renal function impairment precautions
- Dosage guidelines in peritoneal dialysis
- No dosage adjustment for hepatic dysfunction
Overdose effects
- Seizure activity
- Encephalopathy
- Neuromuscular excitability
- Coma
Drug classes
- Third generation Cephalosporins
Reconstitution
- Guidelines for reconstitution
Storage conditions
- Temperature conditions for storage
- Stability of reconstituted solutions