Trum 3 1 gm/vial (IM/IV Injection)

1 gm vial: ৳ 230.00

Medicine Details

Indications

  • Lower Respiratory Tract Infections
  • Skin and Skin Structure Infections
  • Urinary Tract Infections
  • Bacterial Septicemia
  • Bone and Joint Infections
  • Gynecologic Infections
  • Intraabdominal Infections
  • Central Nervous System Infections

Pharmacology

  • Bactericidal action
  • Inhibition of enzymes responsible for cell-wall synthesis
  • Susceptibility to gram-negative organisms
  • Activity against gram-positive organisms
  • Stability to beta-lactamases

Dosage

  • Usual adult dosage of 1 gram every 8 to 12 hours intravenously or intramuscularly
  • Dosage adjustment based on severity of infection and patient's condition
  • Dosage range for adults, elderly, infants, and children
  • Special dosing for urinary tract infections, severe infections, and prophylactic use

Administration

  • Intravenous or deep intramuscular administration
  • Reconstitution with Sterile Water for Injection

Contraindications

  • Hypersensitivity to Ceftazidime or cephalosporin antibiotics

Side Effects

  • Local reactions following IV injection
  • Allergic and gastrointestinal reactions
  • Hypersensitivity reactions
  • Gastrointestinal symptoms
  • Central nervous system reactions

Pregnancy & Lactation

  • Limited data in pregnant women
  • Excretion in human milk
  • Consideration for discontinuing nursing

Precautions & Warnings

  • Dosage reduction in renal insufficiency
  • Caution in patients with history of gastrointestinal disease

Use in Special Populations

  • Dosage adjustment in impaired renal function
  • Use in peritoneal dialysis and continuous ambulatory peritoneal dialysis (CAPD)
  • No dosage adjustment required for patients with hepatic dysfunction

Overdose Effects

  • Symptoms include seizure, encephalopathy, neuromuscular excitability
  • Supportive treatment for acute overdosage

Therapeutic Class

  • Third generation Cephalosporins

Reconstitution

  • Amount of Sterile Water for Injection for different doses

Storage Conditions

  • Storage below 25°C
  • Protected from light and moisture
  • Stability of reconstituted solutions

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