Arixon 1 gm/vial (IM Injection)
1 gm vial: ৳ 190.00
Medicine Details
Category | Details |
---|---|
Generic | Ceftriaxone sodium |
Company | Beximco pharmaceuticals ltd |
Also available as |
Title and Categories
- Arixon
- Antibiotic
- Ceftriaxone
- Parenteral medication
- Broad-spectrum cephalosporin
Indications
- Lower respiratory tract infections
- Acute Bacterial Otitis Media
- Skin and skin structure infections
- Urinary tract infections
- Gonorrhea
- Bacterial Septicemia
- Bone and joint infections
- Meningitis
- Prevention of postoperative infections
- Perioperative prophylaxis of infections associated with surgery
Pharmacology
- Broad-spectrum activity
- Bactericidal
- Interferes with bacterial cell wall synthesis
- Stable in the presence of beta lactamases
- Long plasma elimination half-life
- Non-metabolized in the body
- Highly protein bound
Dosage
- 1-2 gm for adults by intravenous or intramuscular administration
- 250 mg for uncomplicated gonococcal infections
- 1 g for surgical prophylaxis
- 50-75 mg/kg for infants and children
- Duration of therapy: 4-14 days, longer in complicated infections
Administration
- Intramuscular or Intravenous Injection
- Preparation of Solutions
- Administered over 2-4 minutes
- Test dose for patient tolerance
- Maintains potency for at least 6 hours at room temperature
Interaction
- No reported drug interactions
Contraindications
- Hypersensitivity to cephalosporin antibiotics
Side Effects
- Gastro-intestinal effects
- Cutaneous reactions
- Hematologic reactions
- Hepatic reactions
- CNS reactions
- Local phlebitis following intravenous administration
Pregnancy & Lactation
- Safety not established in human pregnancy
- Caution in lactating mothers
Precautions & Warnings
- Risk of anaphylactic shock
- Sonogram findings in the gallbladder
- Regular blood picture checks during prolonged treatment
Use in Special Populations
- Avoid in premature and newborn neonates (up to 28 days of age)
Overdose Effects
- No specific antidote
- Symptomatic treatment
Therapeutic Class
- Third generation Cephalosporins
Storage Conditions
- Store in a cool, dry place (below 30°C)
- Away from light & moisture
- Keep out of the reach of children