Arixon 1 gm/vial (IM Injection)

1 gm vial: ৳ 190.00

Medicine Details

Title and Categories

  • Arixon
  • Antibiotic
  • Ceftriaxone
  • Parenteral medication
  • Broad-spectrum cephalosporin

Indications

  • Lower respiratory tract infections
  • Acute Bacterial Otitis Media
  • Skin and skin structure infections
  • Urinary tract infections
  • Gonorrhea
  • Bacterial Septicemia
  • Bone and joint infections
  • Meningitis
  • Prevention of postoperative infections
  • Perioperative prophylaxis of infections associated with surgery

Pharmacology

  • Broad-spectrum activity
  • Bactericidal
  • Interferes with bacterial cell wall synthesis
  • Stable in the presence of beta lactamases
  • Long plasma elimination half-life
  • Non-metabolized in the body
  • Highly protein bound

Dosage

  • 1-2 gm for adults by intravenous or intramuscular administration
  • 250 mg for uncomplicated gonococcal infections
  • 1 g for surgical prophylaxis
  • 50-75 mg/kg for infants and children
  • Duration of therapy: 4-14 days, longer in complicated infections

Administration

  • Intramuscular or Intravenous Injection
  • Preparation of Solutions
  • Administered over 2-4 minutes
  • Test dose for patient tolerance
  • Maintains potency for at least 6 hours at room temperature

Interaction

  • No reported drug interactions

Contraindications

  • Hypersensitivity to cephalosporin antibiotics

Side Effects

  • Gastro-intestinal effects
  • Cutaneous reactions
  • Hematologic reactions
  • Hepatic reactions
  • CNS reactions
  • Local phlebitis following intravenous administration

Pregnancy & Lactation

  • Safety not established in human pregnancy
  • Caution in lactating mothers

Precautions & Warnings

  • Risk of anaphylactic shock
  • Sonogram findings in the gallbladder
  • Regular blood picture checks during prolonged treatment

Use in Special Populations

  • Avoid in premature and newborn neonates (up to 28 days of age)

Overdose Effects

  • No specific antidote
  • Symptomatic treatment

Therapeutic Class

  • Third generation Cephalosporins

Storage Conditions

  • Store in a cool, dry place (below 30°C)
  • Away from light & moisture
  • Keep out of the reach of children

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