Axon 250 mg/vial (IM Injection)

250 mg vial: ৳ 100.00

Medicine Details

Indications

  • Lower respiratory tract infections
  • Acute Bacterial Otitis Media
  • Skin and skin structure infections
  • Urinary tract infections
  • Gonorrhea
  • Bacterial Septicemia
  • Bone and joint infections
  • Meningitis
  • Prevention of postoperative infections
  • Perioperative prophylaxis of infections associated with surgery

Pharmacology

Ceftriaxone is a 3rd generation broad-spectrum parenteral cephalosporin antibiotic with potent bactericidal activity against a wide range of Gram-positive and Gram-negative organisms.

Dosage

  • Usual dose for adults: 1 to 2 gm by intravenous or intramuscular administration once a day
  • Usual dose for infants and children: 50 to 75 mg/kg intravenous or intramuscular administration once a day

Administration

  • Preparation of Solutions for Intramuscular / Intravenous Injections
  • Injection administered over 2-4 minutes
  • Patient tolerance test recommended before starting treatment

Interaction

No drug interactions reported

Contraindications

Not for patients with a history of hypersensitivity to cephalosporin antibiotics

Side Effects

  • Gastro-intestinal effects including diarrhea, nausea and vomiting
  • Cutaneous reactions including rash, pruritus, urticaria
  • Hematologic reactions including eosinophilia, thrombocytopenia
  • Hepatic reactions including elevations of SGOT or SGPT
  • CNS reactions including nervousness, confusion, sleep disturbances

Pregnancy & Lactation

Not established for safety in human pregnancy, caution in lactating mothers

Precautions & Warnings

  • Anaphylactic shock may occur
  • Monitor the blood picture during prolonged treatment
  • Avoid in neonates if premature and newborn (up to 28 days of age)

Overdose Effects

No specific antidote, treatment should be symptomatic

Therapeutic Class

Third generation Cephalosporins

Storage Conditions

Vial store in a cool, dry place (below 30° C), away from light & moisture

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