Axosin 1 gm/vial (IM Injection)
Medicine Details
| Category | Details |
|---|---|
| Generic | Ceftriaxone sodium |
| Company | Ibn sina pharmaceuticals ltd |
| Also available as |
Indications
- Lower respiratory tract infections
- Acute Bacterial Otitis Media
- Skin and skin structure infections
- Urinary tract infections
- Gonorrhea
- Bacterial Septicemia
- Bone and joint infections
- Meningitis
- Prevention of postoperative infections
- Perioperative prophylaxis of infections associated with surgery
Pharmacology
Ceftriaxone is a 3rd generation broad-spectrum parenteral cephalosporin antibiotic with potent bactericidal activity against a wide range of Gram-positive and Gram-negative organisms. It kills bacteria by interfering with the synthesis of the bacterial cell wall. Ceftriaxone has a high stability in the presence of beta lactamases and a relatively long plasma elimination half-life of about 6 to 9 hours.
Dosage
- Adult
- Infants and Children (01 month or older)
- Pneumonia, Bronchitis, Acute bacterial otitis media, Skin and skin structure infection, Urinary tract infections, Bacterial Septicemia, Bone and joint infections, Meningitis
- Uncomplicated gonococcal infections
- Surgical prophylaxis
- Duration of therapy
Administration
Preparation of Solutions for Intramuscular / Intravenous Injections using Lidocaine HCI 1% injection or Water for injection USP.
Interaction
No drug interactions have been reported.
Contraindications
Not to be given to patients with a history of hypersensitivity to cephalosporin antibiotics.
Side Effects
- Gastro-intestinal effects
- Cutaneous reactions
- Hematologic reactions
- Hepatic reactions
- CNS reactions
- Local phlebitis
Pregnancy & Lactation
Safety in human pregnancy not established. Caution in lactating mothers.
Precautions & Warnings
- Anaphylactic shock
- Gallbladder shadow on sonograms
- Blood picture checking during prolonged treatment
Use in Special Populations
Must not be given to premature and newborn neonates (up to 28 days of age).
Overdose Effects
No specific antidote. Symptomatic treatment for overdosage.
Therapeutic Class
Third generation Cephalosporins
Storage Conditions
Vial should be stored in a cool, dry place (below 30°C), away from light & moisture and out of the reach of children