Axosin 2 gm/vial (IV Injection)
2 gm vial: ৳ 290.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Ceftriaxone sodium |
| Company | Ibn sina pharmaceuticals ltd |
| Also available as |
Indications
- Lower respiratory tract infections
- Acute Bacterial Otitis Media
- Skin and skin structure infections
- Urinary tract infections
- Gonorrhea
- Bacterial Septicemia
- Bone and joint infections
- Meningitis
- Prevention of postoperative infections
- Perioperative prophylaxis of infections associated with surgery
Pharmacology
- Broad-spectrum antibiotic
- Potent bactericidal activity
- Interferes with bacterial cell wall synthesis
- High stability in the presence of beta lactamases
- Long plasma elimination half-life of 6 to 9 hours
- Not metabolized in the body
- Excretion through urine and bile
- Highly protein bound (95%)
Dosage
- Usual dose for adults: 1 to 2 gm by intravenous or intramuscular administration once a day
- Maximum dose for adults: 4 gm/day
- Usual dose for infants and children: 50 to 75 mg/kg intravenous or intramuscular administration once a day
- Maximum dose for infants and children: 2 gm/day
- Duration of therapy: 4 to 14 days
Administration
- Intramuscular injection preparation
- Intravenous injection preparation
- Recommended injection duration and concentration
- Patient tolerance test before treatment
- Solution stability for at least 6 hours at room temperature or 24 hours at 5°C
Interaction
- No reported drug interactions
Contraindications
- Hypersensitivity to cephalosporin antibiotics
Side Effects
- Gastro-intestinal effects
- Cutaneous reactions
- Hematologic reactions
- Hepatic reactions
- CNS reactions
- Rare occurrence of local phlebitis after intravenous administration
Pregnancy & Lactation
- Safety not established in human pregnancy
- Caution advised during lactation
Precautions & Warnings
- Risk of anaphylactic shock
- Possibility of gallbladder sludge
- Regular blood picture checks during prolonged treatment
Use in Special Populations
- Avoid use in neonates if premature or newborn (up to 28 days of age)
Overdose Effects
- No specific antidote
- Symptomatic treatment recommended
Therapeutic Class
- Third generation Cephalosporins
Storage Conditions
- Store in a cool, dry place (below 30°C)
- Protect from light and moisture
- Keep out of the reach of children