Cefixon 1 gm/vial (IV Injection)
1 gm vial: ৳ 200.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Ceftriaxone sodium |
| Company | Techno drugs ltd |
| Also available as |
Indications
- Lower respiratory tract infections
- Acute Bacterial Otitis Media
- Skin and skin structure infections
- Urinary tract infections
- Gonorrhea
- Bacterial Septicemia
- Bone and joint infections
- Meningitis
- Prevention of postoperative infections
- Perioperative prophylaxis of infections associated with surgery
Pharmacology
- Broad-spectrum parenteral cephalosporin antibiotic
- Potent bactericidal activity against a wide range of Gram-positive and Gram-negative organisms
- Interferes with the synthesis of the bacterial cell wall
- Long plasma elimination half-life of about 6 to 9 hours
- Not metabolized in the body
- Highly protein bound (95%)
Dosage
- Usual dose of 1 to 2 gm by intravenous or intramuscular administration once a day
- Different doses for various infections and age groups
- Duration of therapy ranging from 4 to 14 days
- Specific doses for surgical prophylaxis and uncomplicated gonococcal infections
Administration
- Preparation of Solutions for Intramuscular / Intravenous Injections
- Instructions for dissolution in Lidocaine HCI 1% injection or Water for injection
- Administration over 2-4 minutes for intramuscular or intravenous injection
- Recommendation for patient tolerance test before treatment
Interaction
- No reported drug interactions
Contraindications
- Patients with a history of hypersensitivity to cephalosporin antibiotics
Side Effects
- Gastro-intestinal effects including diarrhea, nausea and vomiting
- Cutaneous reactions including rash, pruritus, urticaria
- Hematologic reactions including eosinophilia, thrombocytopenia, leucopenia
- Hepatic reactions including elevations of SGOT or SGPT, bilirubinemia
- CNS reactions including nervousness, confusion, sleep disturbances
- Local phlebitis following intravenous administration
Pregnancy & Lactation
- Safety in human pregnancy has not been established
- Caution advised during lactation
Precautions & Warnings
- Risk of anaphylactic shock
- Possibility of shadows suggesting sludge in the gallbladder
- Regular blood picture checks during prolonged treatment
Use in Special Populations
- Cefixon must not be given to neonates if premature and newborn (up to 28 days of age)
Overdose Effects
- No specific antidote
- Treatment should be symptomatic
Therapeutic Class
- Third generation Cephalosporins
Storage Conditions
- Store in a cool, dry place (below 30°C)
- Keep away from light & moisture
- Keep out of the reach of children