Ceftizone 1 gm/vial (IM Injection)
1 gm vial: ৳ 250.00
Medicine Details
Category | Details |
---|---|
Generic | Ceftriaxone sodium |
Company | Renata limited |
Also available as |
Indications
- Lower respiratory tract infections
- Acute Bacterial Otitis Media
- Skin and skin structure infections
- Urinary tract infections
- Gonorrhea
- Bacterial Septicemia
- Bone and joint infections
- Meningitis
- Prevention of postoperative infections
- Perioperative prophylaxis of infections associated with surgery
Pharmacology
Ceftriaxone is a 3rd generation broad-spectrum parenteral cephalosporin antibiotic with potent bactericidal activity against a wide range of Gram-positive and Gram-negative organisms. It kills bacteria by interfering with the synthesis of the bacterial cell wall. Ceftriaxone has a relatively long plasma elimination half-life, is not metabolized in the body, and is highly protein bound (95%).
Dosage
- Usual dose for adults: 1 to 2 gm by intravenous or intramuscular administration once a day
- Maximum adult dose: 4 gm/day
- Usual dose for infants and children: 50 to 75 mg/kg intravenous or intramuscular administration once a day
- Maximum pediatric dose: 2 gm/day
- Duration of therapy: 4 to 14 days for most infections
Administration
- Preparation of Solutions for Intramuscular Injection
- Preparation of Solutions for Intravenous Injection
- Injection administration guidelines
Interaction
No drug interactions reported
Contraindications
Hypersensitivity to cephalosporin antibiotics
Side Effects
- Gastro-intestinal effects
- Cutaneous reactions
- Hematologic reactions
- Hepatic reactions
- CNS reactions
- Rare occurrence of local phlebitis
Pregnancy & Lactation
Not established for use in pregnancy, caution in lactating mothers
Precautions & Warnings
- Risk of anaphylactic shock
- Potential gallbladder concerns
- Blood picture monitoring during prolonged treatment
Use in Special Populations
Avoid use in premature and newborn neonates
Overdose Effects
No specific antidote, symptomatic treatment
Therapeutic Class
Third generation Cephalosporins
Storage Conditions
Store in a cool, dry place below 30°C, away from light & moisture, keep out of reach of children