Ceftizone 1 gm/vial (IM Injection)

1 gm vial: ৳ 250.00

Medicine Details

Indications

  • Lower respiratory tract infections
  • Acute Bacterial Otitis Media
  • Skin and skin structure infections
  • Urinary tract infections
  • Gonorrhea
  • Bacterial Septicemia
  • Bone and joint infections
  • Meningitis
  • Prevention of postoperative infections
  • Perioperative prophylaxis of infections associated with surgery

Pharmacology

Ceftriaxone is a 3rd generation broad-spectrum parenteral cephalosporin antibiotic with potent bactericidal activity against a wide range of Gram-positive and Gram-negative organisms. It kills bacteria by interfering with the synthesis of the bacterial cell wall. Ceftriaxone has a relatively long plasma elimination half-life, is not metabolized in the body, and is highly protein bound (95%).

Dosage

  • Usual dose for adults: 1 to 2 gm by intravenous or intramuscular administration once a day
  • Maximum adult dose: 4 gm/day
  • Usual dose for infants and children: 50 to 75 mg/kg intravenous or intramuscular administration once a day
  • Maximum pediatric dose: 2 gm/day
  • Duration of therapy: 4 to 14 days for most infections

Administration

  • Preparation of Solutions for Intramuscular Injection
  • Preparation of Solutions for Intravenous Injection
  • Injection administration guidelines

Interaction

No drug interactions reported

Contraindications

Hypersensitivity to cephalosporin antibiotics

Side Effects

  • Gastro-intestinal effects
  • Cutaneous reactions
  • Hematologic reactions
  • Hepatic reactions
  • CNS reactions
  • Rare occurrence of local phlebitis

Pregnancy & Lactation

Not established for use in pregnancy, caution in lactating mothers

Precautions & Warnings

  • Risk of anaphylactic shock
  • Potential gallbladder concerns
  • Blood picture monitoring during prolonged treatment

Use in Special Populations

Avoid use in premature and newborn neonates

Overdose Effects

No specific antidote, symptomatic treatment

Therapeutic Class

Third generation Cephalosporins

Storage Conditions

Store in a cool, dry place below 30°C, away from light & moisture, keep out of reach of children

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