Ceftizone 250 mg/vial (IV Injection)

250 mg vial: ৳ 100.38

Medicine Details

Category Details
Generic Ceftriaxone sodium
Company Renata limited
Also available as
Ceftizone 250 mg injection Ceftizone 500 mg injection Ceftizone 1 gm injection Ceftizone 500 mg injection Ceftizone 1 gm injection Ceftizone 2 gm injection

Indications

  • Lower respiratory tract infections
  • Acute Bacterial Otitis Media
  • Skin and skin structure infections
  • Urinary tract infections
  • Gonorrhea
  • Bacterial Septicemia
  • Bone and joint infections
  • Meningitis
  • Prevention of postoperative infections
  • Perioperative prophylaxis of infections associated with surgery

Pharmacology

  • Broad-spectrum parenteral cephalosporin antibiotic
  • Potent bactericidal activity
  • Interferes with synthesis of bacterial cell wall
  • Stable in the presence of beta lactamases
  • Long plasma elimination half-life
  • Not metabolized in the body
  • Highly protein bound (95%)

Dosage

  • 1 to 2 gm by intravenous or intramuscular administration once a day
  • Maximum dose: 4 gm/day for adults
  • 50 to 75 mg/kg intravenous or intramuscular administration once a day for infants and children
  • Usual duration of therapy: 4 to 14 days

Administration

  • Preparation of Solutions for Intramuscular / Intravenous Injections
  • Recommended administration over 2-4 minutes
  • Freshly reconstituted solution is recommended

Interaction

  • No reported drug interactions

Contraindications

  • Hypersensitivity to cephalosporin antibiotics

Side Effects

  • Gastro-intestinal effects including diarrhea, nausea, and vomiting
  • Cutaneous reactions including rash, pruritus, and urticaria
  • Hematologic reactions including eosinophilia, thrombocytopenia, and leucopenia
  • Hepatic reactions including elevations of SGOT or SGPT
  • CNS reactions including nervousness, confusion, and headache
  • Local phlebitis occurs rarely following intravenous administration

Pregnancy & Lactation

  • Safety in human pregnancy not established
  • Caution should be exercised when administered to a lactating mother

Precautions & Warnings

  • Anaphylactic shock cannot be ruled out
  • Monitoring of blood picture during prolonged treatment

Use in Special Populations

  • Not to be given to neonates if premature and newborn (up to 28 days of age)

Overdose Effects

  • No specific antidote
  • Symptomatic treatment

Therapeutic Class

  • Third generation Cephalosporins

Storage Conditions

  • Store in a cool, dry place below 30°C
  • Away from light and moisture
  • Keep out of the reach of children

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