Ceftizone 2 gm/vial (IV Injection)

2 gm vial: ৳ 400.00

Medicine Details

Category Details
Generic Ceftriaxone sodium
Company Renata limited
Also available as
Ceftizone 250 mg injection Ceftizone 500 mg injection Ceftizone 1 gm injection Ceftizone 250 mg injection Ceftizone 500 mg injection Ceftizone 1 gm injection

Indications

  • Lower respiratory tract infections
  • Acute Bacterial Otitis Media
  • Skin and skin structure infections
  • Urinary tract infections
  • Gonorrhea
  • Bacterial Septicemia
  • Bone and joint infections
  • Meningitis
  • Prevention of postoperative infections
  • Perioperative prophylaxis of infections associated with surgery

Pharmacology

  • Broad-spectrum antibiotic
  • Bactericidal activity
  • Interferes with bacterial cell wall synthesis
  • Stable in the presence of beta lactamases
  • Long plasma elimination half-life
  • Not metabolized in the body
  • Excretion in urine and bile
  • Highly protein bound (95%)

Dosage

  • Adult dosage: 1 to 2 gm by intravenous or intramuscular administration once a day
  • Maximum adult dose: 4 gm/day
  • Infant and children dosage: 50 to 75 mg/kg intravenous or intramuscular administration once a day
  • Usual duration of therapy: 4 to 14 days

Administration

  • Preparation for intramuscular / intravenous injections
  • Injection should be administered over 2-4 minutes
  • Patient tolerance test before starting treatment

Interaction

  • No reported drug interactions

Contraindications

  • Hypersensitivity to cephalosporin antibiotics

Side Effects

  • Gastro-intestinal effects
  • Cutaneous reactions
  • Hematologic reactions
  • Hepatic reactions
  • CNS reactions
  • Local phlebitis

Pregnancy & Lactation

  • Safety in human pregnancy not established
  • Caution in lactating mothers

Precautions & Warnings

  • Anaphylactic shock
  • Gallbladder sludge
  • Blood picture checks during prolonged treatment

Use in Special Populations

  • Not recommended for neonates if premature

Overdose Effects

  • No specific antidote

Therapeutic Class

  • Third generation Cephalosporins

Storage Conditions

  • Store in a cool, dry place below 30°C
  • Keep away from light and moisture
  • Keep out of the reach of children

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