Ceftron 250 mg/vial (IM Injection)

250 mg vial: ৳ 130.00

Medicine Details

Category Details
Generic Ceftriaxone sodium
Company Square pharmaceuticals plc
Also available as
Ceftron 500 mg injection Ceftron 1 gm injection Ceftron 250 mg injection Ceftron 500 mg injection Ceftron 1 gm injection Ceftron 2 gm injection

Indications

  • Lower respiratory tract infections
  • Acute Bacterial Otitis Media
  • Skin and skin structure infections
  • Urinary tract infections
  • Gonorrhea
  • Bacterial Septicemia
  • Bone and joint infections
  • Meningitis
  • Prevention of postoperative infections
  • Perioperative prophylaxis of infections associated with surgery

Pharmacology

Ceftriaxone is a 3rd generation broad-spectrum parenteral cephalosporin antibiotic with bactericidal activity against a wide range of Gram-positive and Gram-negative organisms. It interferes with the synthesis of the bacterial cell wall and has a relatively long plasma elimination half-life of about 6 to 9 hours.

Dosage

  • 1 to 2 gm by intravenous or intramuscular administration once a day (or in equally divided doses twice a day)
  • 250 mg IM as a single dose for uncomplicated gonococcal infections
  • 1 g IV as a single dose 30 to 120 minutes before surgery for surgical prophylaxis
  • 50 to 75 mg/kg intravenous or intramuscular administration once a day for infants and children (01 month or older)

Administration

  • Preparation of Solutions for Intramuscular/Intravenous Injections
  • 250 mg or 500 mg Ceftriaxone should be dissolved in 2 ml Lidocaine HCI 1% injection for Intramuscular Injection
  • 250 mg or 500 mg Ceftriaxone should be dissolved in 5 ml of Water for injection for Intravenous Injection
  • Injection should be administered over 2-4 minutes for Intramuscular or Intravenous injection or by tubing infusion over a period of 30 minutes

Interaction

No drug interactions reported

Contraindications

Patients with a history of hypersensitivity to cephalosporin antibiotics

Side Effects

  • Gastro-intestinal effects including diarrhea, nausea, vomiting
  • Cutaneous reactions including rash, pruritus, urticaria
  • Hematologic reactions including eosinophilia, thrombocytopenia, leucopenia
  • Hepatic reactions including elevations of SGOT or SGPT, bilirubinemia
  • CNS reactions including nervousness, confusion, headache

Pregnancy & Lactation

Not established for safety in human pregnancy; caution in lactating mothers

Precautions & Warnings

  • Anaphylactic shock cannot be ruled out
  • Shadows suggesting sludge have been detected by sonograms of the gallbladder
  • Blood picture should be checked at regular intervals during prolonged treatment

Use in Special Populations

Ceftron must not be given to neonates if premature and newborn (up to 28 days of age)

Overdose Effects

No specific antidote; treatment should be symptomatic

Therapeutic Class

Third generation Cephalosporins

Storage Conditions

Store in a cool, dry place (below 30°C), away from light & moisture; keep out of reach of children

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