Ceftron 2 gm/vial (IV Injection)

2 gm vial: ৳ 400.00

Medicine Details

Category	Details
Generic	Ceftriaxone sodium
Company	Square pharmaceuticals plc
Also available as	Ceftron 250 mg injection Ceftron 500 mg injection Ceftron 1 gm injection Ceftron 250 mg injection Ceftron 500 mg injection Ceftron 1 gm injection

Indications

Lower respiratory tract infections
Acute Bacterial Otitis Media
Skin and skin structure infections
Urinary tract infections
Gonorrhea
Bacterial Septicemia
Bone and joint infections
Meningitis
Prevention of postoperative infections
Perioperative prophylaxis of infections associated with surgery

Pharmacology

Ceftriaxone is a 3rd generation broad-spectrum parenteral cephalosporin antibiotic with potent bactericidal activity against a wide range of Gram-positive and Gram-negative organisms. It interferes with the synthesis of the bacterial cell wall and has a relatively long plasma elimination half-life of 6 to 9 hours. It is not metabolized in the body and is highly protein bound (95%).

Dosage

Adult:
- 1 to 2 gm by intravenous or intramuscular administration once a day (or in equally divided doses twice a day)
Infants and Children (01 month or older):
- 50 to 75 mg/kg intravenous or intramuscular administration once a day (or in equally divided doses twice a day)

Administration

Intramuscular Injection: 250 mg or 500 mg Ceftriaxone should be dissolved in Lidocaine HCI 1% injection
Intravenous Injection: 250 mg or 500 mg Ceftriaxone should be dissolved in Water for injection
Injection should be administered over 2-4 minutes, by Intramuscular or Intravenous injection or by tubing infusion over a period of 30 minutes

Interaction

No drug interactions have been reported.

Contraindications

Ceftriaxone should not be given to patients with a history of hypersensitivity to cephalosporin antibiotics.

Side Effects

Gastro-intestinal effects
Cutaneous reactions
Hematologic reactions
Hepatic reactions
CNS reactions
Local phlebitis following intravenous administration

Pregnancy & Lactation

Safety in human pregnancy has not been established. Caution should be exercised when Ceftriaxone is administered to a lactating mother.

Precautions & Warnings

Anaphylactic shock
Shadows suggesting sludge in the gallbladder
Blood picture should be checked at regular intervals during prolonged treatment

Use in Special Populations

Ceftriaxone must not be given to neonates if premature and newborn (up to 28 days of age).

Overdose Effects

There is no specific antidote. Treatment of overdosage should be symptomatic.

Therapeutic Class

Third generation Cephalosporins

Storage Conditions

Store in a cool, dry place (below 30°C), away from light & moisture. Keep out of the reach of children.