Eracef 1 gm/vial (IV Injection)
1 gm vial: ৳ 190.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Ceftriaxone sodium |
| Company | Popular pharmaceuticals ltd |
| Also available as |
Indications
- Lower respiratory tract infections
- Acute Bacterial Otitis Media
- Skin and skin structure infections
- Urinary tract infections
- Gonorrhea
- Bacterial Septicemia
- Bone and joint infections
- Meningitis
- Prevention of postoperative infections
- Perioperative prophylaxis of infections associated with surgery
Pharmacology
- Broad-spectrum parenteral cephalosporin antibiotic
- Bactericidal activity against Gram-positive and Gram-negative organisms
- Interferes with the synthesis of the bacterial cell wall
- High degree of stability in the presence of beta lactamases
- Relatively long plasma elimination half-life of 6 to 9 hours
- Not metabolized in the body
- Highly protein bound (95%)
Dosage
- Usual dose of 1 to 2 gm by intravenous or intramuscular administration once a day
- Different doses for various infections in adults and infants/children
- Maximum dose of 4 gm/day for certain infections
- Duration of therapy is 4 to 14 days
Administration
- Preparation and dissolution for intramuscular/intravenous injections
- Administration over 2-4 minutes
- Test dose recommended before starting treatment
- Potency maintained for at least 6 hours at room temperature or 24 hours at 5°C
Interaction
- No reported drug interactions
Contraindications
- Not to be given to patients with a history of hypersensitivity to cephalosporin antibiotics
Side Effects
- Gastro-intestinal effects including diarrhea, nausea and vomiting
- Cutaneous reactions including rash, pruritus, urticaria
- Hematologic reactions including eosinophilia, thrombocytopenia
- Hepatic reactions including elevations of SGOT or SGPT, bilirubinemia
- CNS reactions including nervousness, confusion, headache
- Local phlebitis occurs rarely following intravenous administration
Pregnancy & Lactation
- Safety in human pregnancy not established
- Caution advised when administered to lactating mother
Precautions & Warnings
- Potential for anaphylactic shock
- Occasional detection of shadows in sonograms of the gallbladder
- Regular blood picture checks during prolonged treatment
Use in Special Populations
- Not to be given to neonates if premature and newborn (up to 28 days of age)
Overdose Effects
- No specific antidote
- Treatment should be symptomatic
Therapeutic Class
- Third generation Cephalosporins
Storage Conditions
- Store vial in a cool, dry place (below 30°C)
- Away from light and moisture
- Keep out of the reach of children