Exephin 1 gm/vial (IM Injection)

1 gm vial: ৳ 190.00

Medicine Details

Category	Details
Generic	Ceftriaxone sodium
Company	Incepta pharmaceuticals ltd
Also available as	Exephin 250 mg injection Exephin 500 mg injection Exephin 250 mg injection Exephin 500 mg injection Exephin 1 gm injection Exephin 2 gm injection

Indications

Lower respiratory tract infections
Acute Bacterial Otitis Media
Skin and skin structure infections
Urinary tract infections
Gonorrhea
Bacterial Septicemia
Bone and joint infections
Meningitis
Prevention of postoperative infections
Perioperative prophylaxis of infections associated with surgery

Pharmacology

Ceftriaxone is a 3rd generation broad-spectrum parenteral cephalosporin antibiotic with potent bactericidal activity against a wide range of Gram-positive and Gram-negative organisms. It kills bacteria by interfering with the synthesis of the bacterial cell wall.

Dosage

Adult dose: 1 to 2 gm by intravenous or intramuscular administration once a day
Children's dose: 50 to 75 mg/kg intravenous or intramuscular administration once a day

Administration

Preparation for Intramuscular Injection:
- 250 mg or 500 mg Ceftriaxone dissolved in Lidocaine HCI 1% injection
- 1 g Ceftriaxone in 3.5 ml of Lidocaine HCI 1% injection
Preparation for Intravenous Injection:
- 250 mg or 500 mg Ceftriaxone dissolved in Water for injection
- 1 g Ceftriaxone in 10 ml of Water for injection USP
- 2 g Ceftriaxone in 20 ml of Water for injection

Interaction

No drug interactions reported

Contraindications

Not to be given to patients with a history of hypersensitivity to cephalosporin antibiotics

Side Effects

Gastro-intestinal effects
Cutaneous reactions
Hematologic reactions
Hepatic reactions
CNS reactions
Local phlebitis rare following intravenous administration

Pregnancy & Lactation

Safety in human pregnancy not established. Use in pregnancy only if absolutely indicated. Exercise caution when administered to a lactating mother.

Precautions & Warnings

Potential for anaphylactic shock
Shadows suggesting sludge have been detected by sonograms of the gallbladder
Blood picture should be checked during prolonged treatment

Use in Special Populations

Must not be given to neonates if premature and newborn (up to 28 days of age)

Overdose Effects

No specific antidote. Treatment should be symptomatic.

Therapeutic Class

Third generation Cephalosporins

Storage Conditions

Store in a cool, dry place (below 30°C), away from light & moisture. Keep out of the reach of children.