G-Ceftriax 250 mg/vial (IV Injection)

250 mg vial: ৳ 50.00

Medicine Details

Category	Details
Generic	Ceftriaxone sodium
Company	Gonoshasthaya pharma ltd
Also available as	G ceftriax 250 mg injection G ceftriax 500 mg injection G ceftriax 1 gm injection G ceftriax 500 mg injection G ceftriax 1 gm injection G ceftriax 2 gm injection

Indications

Lower respiratory tract infections
Acute Bacterial Otitis Media
Skin and skin structure infections
Urinary tract infections
Gonorrhea
Bacterial Septicemia
Bone and joint infections
Meningitis
Prevention of postoperative infections
Perioperative prophylaxis of infections associated with surgery

Pharmacology

Ceftriaxone is a 3rd generation broad-spectrum parenteral cephalosporin antibiotic with potent bactericidal activity against a wide range of Gram-positive and Gram-negative organisms. It kills bacteria by interfering with the synthesis of the bacterial cell wall and has a long plasma elimination half-life of about 6 to 9 hours.

Dosage

Adult:
- 1 to 2 gm by intravenous or intramuscular administration once a day
- Maximum dose: 4 gm/day
Infants and Children (01 month or older):
- 50 to 75 mg/kg intravenous or intramuscular administration once a day
- Maximum dose: 2 gm/day
- Duration of therapy: 4 to 14 days

Administration

Preparation of Solutions:
- Intramuscular Injection: 250 mg or 500 mg Ceftriaxone should be dissolved in Lidocaine HCI 1% injection
- Intravenous Injection: 250 mg or 500 mg Ceftriaxone should be dissolved in Water for injection
- Recommended administration over 2-4 minutes for intramuscular or intravenous injection

Interaction

No drug interactions reported

Contraindications

Should not be given to patients with a history of hypersensitivity to cephalosporin antibiotics

Side Effects

Gastro-intestinal effects including diarrhea, nausea and vomiting
Cutaneous reactions including rash, pruritus, urticaria
Hepatic reactions including elevations of SGOT or SGPT
Local phlebitis occurs rarely following intravenous administration

Pregnancy & Lactation

Safety not established in human pregnancy. Caution should be exercised when administered to a lactating mother

Precautions & Warnings

Anaphylactic shock cannot be ruled out
Shadows suggesting sludge have been detected by sonograms of the gallbladder
Blood picture should be checked at regular intervals during prolonged treatment

Use in Special Populations

Must not be given to premature neonates and newborns up to 28 days of age

Overdose Effects

No specific antidote. Treatment should be symptomatic

Therapeutic Class

Third generation Cephalosporins

Storage Conditions

Vial store in a cool, dry place (below 30° C), away from light & moisture