G-Ceftriax 500 mg/vial (IV Injection)

500 mg vial: ৳ 80.00

Medicine Details

Indications

  • Lower respiratory tract infections
  • Acute Bacterial Otitis Media
  • Skin and skin structure infections
  • Urinary tract infections
  • Gonorrhea
  • Bacterial Septicemia
  • Bone and joint infections
  • Meningitis
  • Prevention of postoperative infections
  • Perioperative prophylaxis of infections associated with surgery

Pharmacology

  • Broad-spectrum antibacterial
  • Potent bactericidal activity
  • Interferes with bacterial cell wall synthesis
  • Long plasma elimination half-life
  • High stability in the presence of beta-lactamases
  • Not metabolized in the body
  • Highly protein bound

Dosage

  • Usual dose for adults: 1 to 2 gm by intravenous or intramuscular administration once a day
  • Maximum dose for adults: 4 gm/day
  • Usual dose for infants and children: 50 to 75 mg/kg intravenous or intramuscular administration once a day
  • Maximum dose for infants and children: 2 gm/day
  • Administration duration: 4 to 14 days

Administration

  • Preparation for intramuscular / intravenous injections
  • Administered over 2-4 minutes by intramuscular or intravenous injection
  • Test dose for patient tolerance

Interaction

No drug interactions reported

Contraindications

Hypersensitivity to cephalosporin antibiotics

Side Effects

  • Gastrointestinal effects
  • Cutaneous reactions
  • Hematologic reactions
  • Hepatic reactions
  • CNS reactions
  • Local phlebitis

Pregnancy & Lactation

  • Not established safety in human pregnancy
  • Caution in lactating mothers

Precautions & Warnings

  • Anaphylactic shock
  • Sludge in gallbladder
  • Blood picture checks during prolonged treatment

Use in Special Populations

Not to be given to premature and newborn neonates

Overdose Effects

No specific antidote. Symptomatic treatment

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