Amocal-AT 5 mg+50 mg (Tablet)

Unit Price: ৳ 6.02 (3 x 14: ৳ 252.84)
Strip Price: ৳ 84.28

Medicine Details

Category Details
Generic Amlodipine besilate atenolol
Company Opsonin pharma ltd

Title

  • Amlodipine and Atenolol 5/25 mg Tablet

Categories

  • Medicine
  • Antihypertensive
  • Cardiovascular medication

Description

  • Combination medication for essential hypertension
  • Contains dihydropyridine calcium antagonist (Amlodipine) and cardioselective beta-blocker (Atenolol)
  • Recommended dosage of 5/25 mg tablet once daily
  • Potential use post myocardial infarction (MI)
  • Indicated for refractory angina pectoris when nitrate therapy has failed
  • Storage conditions: Below 30°C, away from light and moisture
  • Contraindicated in sinus bradycardia, heart block, cardiogenic shock, hypotension, congestive heart failure
  • Potential side effects: fatigue, headache, edema, nausea, drowsiness, anxiety, depression
  • Usage precautions for patients with airway obstruction, renal impairment, and hepatic impairment

Dosage

  • Recommended dosage: 5/25 mg tablet once daily
  • Dosage may be individualized
  • Dosage may be increased to 5/25 mg two tablets daily as advised by physicians

Interaction

  • Interaction with disopyramide: Atenolol reduces disopyramide clearance by 20%
  • Interaction with ampicillin: May reduce Atenolol levels at doses of 1 gm and above
  • Interaction with oral antidiabetics and insulin: Beta-blockers may decrease tissue sensitivity to insulin and inhibit insulin secretion

Contraindications

  • Contraindicated in hypersensitivity to either component
  • Contraindicated in poor left ventricular function
  • Not to be used in pregnancy and lactation, unless the expected benefit outweighs potential fetal risk

Side Effects

  • Well-tolerated combination with side-effects including fatigue, headache, edema, nausea, drowsiness, anxiety, depression

Pregnancy & Lactation

  • Use during pregnancy only if expected benefit outweighs potential fetal risk
  • Should not be used by nursing mothers, if necessary, breastfeeding should be stopped

Precautions & Warnings

  • Use with caution in patients with airway obstruction
  • Can be used in patients with renal impairment, caution if creatinine clearance is less than 30 ml/min
  • Caution necessary in severe liver damage due to prolongation of Amlodipine elimination half-life
  • Patients should be warned against abrupt discontinuation

Overdose Effects

  • Hypotension and less frequently congestive cardiac failure may occur
  • Unabsorbed drugs may be removed by gastric lavage or administration of activated charcoal
  • Symptomatic treatment is suggested

Therapeutic Class

  • Combined antihypertensive preparations

Storage Conditions

  • Keep below 30°C temperature
  • Store away from light and moisture
  • Keep out of the reach of children

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