Inoxon 500 mg/vial (IM Injection)
500 mg vial: ৳ 120.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Ceftriaxone sodium |
| Company | Rephco pharmaceuticals ltd |
| Also available as |
Indications
- Lower respiratory tract infections
- Acute Bacterial Otitis Media
- Skin and skin structure infections
- Urinary tract infections
- Gonorrhea
- Bacterial Septicemia
- Bone and joint infections
- Meningitis
- Prevention of postoperative infections
- Perioperative prophylaxis of infections associated with surgery
Pharmacology
- Broad-spectrum parenteral cephalosporin antibiotic
- Potent bactericidal activity
- Interferes with synthesis of bacterial cell wall
- High stability in the presence of beta lactamases
- Long plasma elimination half-life of about 6 to 9 hours
- Not metabolized in the body
- Excretion in urine and feces
- Highly protein bound (95%)
Dosage
- Adult dose of 1 to 2 gm by intravenous or intramuscular administration once a day
- Maximum adult dose of 4 gm/day
- Infants and Children dose of 50 to 75 mg/kg intravenous or intramuscular administration once a day
- Maximum infants and children dose of 2 gm/day
- Duration of therapy typically 4 to 14 days
Administration
- Preparation of Solutions for Intramuscular / Intravenous Injections
- Intramuscular Injection using Lidocaine HCI 1% injection
- Intravenous Injection using Water for injection
- Injection should be administered over 2-4 minutes
- Freshly reconstituted solution is recommended
Interaction
- No drug interactions reported
Contraindications
- Not to be given to patients with hypersensitivity to cephalosporin antibiotics
Side Effects
- Gastro-intestinal effects
- Cutaneous reactions
- Hematologic reactions
- Hepatic reactions
- CNS reactions
- Local phlebitis following intravenous administration
Pregnancy & Lactation
- Safety in human pregnancy not established
- Caution advised during lactation
Precautions & Warnings
- Potential for anaphylactic shock
- Monitoring blood picture during prolonged treatment
Use in Special Populations
- Not to be given to neonates if premature and newborn (up to 28 days of age)
Overdose Effects
- No specific antidote. Symptomatic treatment advised
Therapeutic Class
- Third generation Cephalosporins
Storage Conditions
- Store in a cool, dry place (below 30°C)
- Keep vial away from light & moisture
- Keep out of the reach of children