Inoxon 1 gm/vial (IV Injection)
1 gm vial: ৳ 160.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Ceftriaxone sodium |
| Company | Rephco pharmaceuticals ltd |
| Also available as |
Indications
- Lower respiratory tract infections
- Acute Bacterial Otitis Media
- Skin and skin structure infections
- Urinary tract infections
- Gonorrhea
- Bacterial Septicemia
- Bone and joint infections
- Meningitis
- Prevention of postoperative infections
- Perioperative prophylaxis of infections associated with surgery
Pharmacology
- Broad-spectrum parenteral cephalosporin antibiotic
- Potent bactericidal activity against a wide range of Gram-positive and Gram-negative organisms
- Interferes with the synthesis of the bacterial cell wall
- High degree of stability in the presence of beta lactamases
- Relatively long plasma elimination half-life of about 6 to 9 hours
- Not metabolized in the body
- Excreted unchanged in the urine
Dosage
- Usual adult dose: 1 to 2 gm by intravenous or intramuscular administration once a day
- Maximum adult dose: 4 gm/day
- Usual pediatric dose: 50 to 75 mg/kg intravenous or intramuscular administration once a day
- Maximum pediatric dose: 2 gm/day
- Duration of therapy: 4 to 14 days
Administration
- Preparation of Solutions for Intramuscular / Intravenous Injections
- Freshly reconstituted solution is recommended
- Patient tolerance test by administration of a test dose
Interaction
- No drug interactions reported
Contraindications
- Hypersensitivity to cephalosporin antibiotics
Side Effects
- Gastrointestinal effects including diarrhea, nausea, vomiting
- Cutaneous reactions including rash, pruritus, urticaria
- Hematologic reactions including eosinophilia, thrombocytopenia
- Hepatic reactions including elevations of SGOT or SGPT
- CNS reactions including nervousness, confusion, sleep disturbances
- Local phlebitis occurs rarely following intravenous administration
Pregnancy & Lactation
- Safety not established in human pregnancy
- Caution should be exercised when administered to a lactating mother
Precautions & Warnings
- Anaphylactic shock may occur
- Gallbladder sludge may be detected
- Blood picture should be checked during prolonged treatment
Use in Special Populations
- Not recommended for premature and newborn neonates
Overdose Effects
- No specific antidote
- Treatment should be symptomatic
Therapeutic Class
- Third generation Cephalosporins
Storage Conditions
- Store in a cool, dry place below 30°C
- Keep away from light and moisture
- Keep out of the reach of children