Odatrix 1 gm/vial (IV Injection)
1 gm vial: ৳ 160.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Ceftriaxone sodium |
| Company | Unimed unihealth pharmaceuticals ltd |
| Also available as |
Indications
- Lower respiratory tract infections
- Acute Bacterial Otitis Media
- Skin and skin structure infections
- Urinary tract infections
- Gonorrhea
- Bacterial Septicemia
- Bone and joint infections
- Meningitis
- Prevention of postoperative infections
- Perioperative prophylaxis of infections associated with surgery
Pharmacology
- Broad-spectrum parenteral cephalosporin antibiotic
- Bactericidal activity against Gram-positive and Gram-negative organisms
- Interferes with synthesis of bacterial cell wall
- High stability in the presence of beta lactamases
- Long plasma elimination half-life of 6 to 9 hours
- Not metabolized in the body
- Approximately 40-65% excreted unchanged in urine
Dosage
- Usual adult dose: 1 to 2 gm by IV or IM once a day
- Maximum adult dose: 4 gm/day
- Usual pediatric dose: 50 to 75 mg/kg by IV or IM once a day
- Maximum pediatric dose: 2 gm/day
- Duration of therapy: 4 to 14 days or more in complicated infections
Administration
- Requires intramuscular or intravenous injection
- Preparation of solutions for injections
- Injection administered over 2-4 minutes or by tubing infusion over 30 minutes
- Patient tolerance test recommended before treatment
Interaction
- No reported drug interactions
Contraindications
- Not to be given to patients with history of hypersensitivity to cephalosporin antibiotics
Side Effects
- Gastro-intestinal effects
- Cutaneous reactions
- Hematologic reactions
- Hepatic reactions
- CNS reactions
- Local phlebitis following intravenous administration
- Rare occurrence of local phlebitis
Pregnancy & Lactation
- Safety in human pregnancy not established
- Caution advised when administered to lactating mother
Precautions & Warnings
- Anaphylactic shock as with other cephalosporins
- Need for immediate countermeasures in case of anaphylactic shock
- Monitoring blood picture during prolonged treatment
Use in Special Populations
- Not to be given to neonates if premature or up to 28 days old
Overdose Effects
- No specific antidote
- Treatment should be symptomatic
Therapeutic Class
- Third generation Cephalosporins
Storage Conditions
- Store in a cool, dry place below 30°C
- Keep away from light and moisture
- Keep out of reach of children