Odatrix 1 gm/vial (IV Injection)

1 gm vial: ৳ 160.00

Medicine Details

Category Details
Generic Ceftriaxone sodium
Company Unimed unihealth pharmaceuticals ltd
Also available as
Odatrix 500 mg injection Odatrix 2 gm injection

Indications

  • Lower respiratory tract infections
  • Acute Bacterial Otitis Media
  • Skin and skin structure infections
  • Urinary tract infections
  • Gonorrhea
  • Bacterial Septicemia
  • Bone and joint infections
  • Meningitis
  • Prevention of postoperative infections
  • Perioperative prophylaxis of infections associated with surgery

Pharmacology

  • Broad-spectrum parenteral cephalosporin antibiotic
  • Bactericidal activity against Gram-positive and Gram-negative organisms
  • Interferes with synthesis of bacterial cell wall
  • High stability in the presence of beta lactamases
  • Long plasma elimination half-life of 6 to 9 hours
  • Not metabolized in the body
  • Approximately 40-65% excreted unchanged in urine

Dosage

  • Usual adult dose: 1 to 2 gm by IV or IM once a day
  • Maximum adult dose: 4 gm/day
  • Usual pediatric dose: 50 to 75 mg/kg by IV or IM once a day
  • Maximum pediatric dose: 2 gm/day
  • Duration of therapy: 4 to 14 days or more in complicated infections

Administration

  • Requires intramuscular or intravenous injection
  • Preparation of solutions for injections
  • Injection administered over 2-4 minutes or by tubing infusion over 30 minutes
  • Patient tolerance test recommended before treatment

Interaction

  • No reported drug interactions

Contraindications

  • Not to be given to patients with history of hypersensitivity to cephalosporin antibiotics

Side Effects

  • Gastro-intestinal effects
  • Cutaneous reactions
  • Hematologic reactions
  • Hepatic reactions
  • CNS reactions
  • Local phlebitis following intravenous administration
  • Rare occurrence of local phlebitis

Pregnancy & Lactation

  • Safety in human pregnancy not established
  • Caution advised when administered to lactating mother

Precautions & Warnings

  • Anaphylactic shock as with other cephalosporins
  • Need for immediate countermeasures in case of anaphylactic shock
  • Monitoring blood picture during prolonged treatment

Use in Special Populations

  • Not to be given to neonates if premature or up to 28 days old

Overdose Effects

  • No specific antidote
  • Treatment should be symptomatic

Therapeutic Class

  • Third generation Cephalosporins

Storage Conditions

  • Store in a cool, dry place below 30°C
  • Keep away from light and moisture
  • Keep out of reach of children

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