Oricef 500 mg/vial (IM Injection)

500 mg vial: ৳ 200.00

Medicine Details

Category Details
Generic Ceftriaxone sodium
Company Healthcare pharmaceuticals ltd
Also available as
Oricef 250 mg injection Oricef 1 gm injection Oricef 250 mg injection Oricef 500 mg injection Oricef 1 gm injection Oricef 2 gm injection

Title

Oricef

Categories

  • Antibiotic
  • Medication
  • Pharmaceutical

Description

Oricef is a 3rd generation broad-spectrum parenteral cephalosporin antibiotic indicated for treating lower respiratory tract infections, acute bacterial otitis media, skin and skin structure infections, urinary tract infections, gonorrhea, bacterial septicemia, bone and joint infections, meningitis, prevention of postoperative infections, and perioperative prophylaxis of infections associated with surgery.

Attributes

  • Indications:
    • Lower respiratory tract infections
    • Acute Bacterial Otitis Media
    • Skin and skin structure infections
    • Urinary tract infections
    • Gonorrhea
    • Bacterial Septicemia
    • Bone and joint infections
    • Meningitis
    • Prevention of postoperative infections
    • Perioperative prophylaxis of infections associated with surgery
  • Pharmacology: Ceftriaxone is a broad-spectrum cephalosporin antibiotic with potent bactericidal activity against a wide range of Gram-positive and Gram-negative organisms. It interferes with the synthesis of the bacterial cell wall. It has a long plasma elimination half-life, high stability in the presence of beta lactamases, and is not metabolized in the body.
  • Dosage:
    • Adult:
      • Usual Dose: 1 to 2 gm by intravenous or intramuscular administration once a day (or in equally divided doses twice a day)
      • Maximum Dose: 4 gm/day
      • Other Specific Doses:
        • Uncomplicated gonococcal infections: 250 mg IM as a single dose
        • Surgical prophylaxis: 1 g IV as a single dose 30 to 120 minutes before surgery
    • Infants and Children (01 month or older):
      • Usual Dose: 50 to 75 mg/kg intravenous or intramuscular administration once a day (or in equally divided doses twice a day)
      • Maximum Dose: 2 gm/day
      • Duration of Therapy: 4 to 14 days; in complicated infections, longer therapy may be required
  • Administration:
    • Intramuscular Injection:
      • 250 mg or 500 mg Ceftriaxone should be dissolved in Lidocaine HCI 1% injection
      • 1 g Ceftriaxone in 3.5 ml of Lidocaine HCI 1% injection
    • Intravenous Injection:
      • 250 mg or 500 mg Ceftriaxone should be dissolved in Water for injection
      • 1 g Ceftriaxone in 10 ml of Water for injection USP
      • 2 g Ceftriaxone in 20 ml of Water for injection
    • Injection Duration: 2-4 minutes for Intramuscular or Intravenous injection; 30 minutes for tubing infusion
    • Test Dose: Patient tolerance test should be checked by administration of a test dose
  • Interaction: No drug interactions reported
  • Contraindications: Patients with a history of hypersensitivity to cephalosporin antibiotics
  • Side Effects:
    • Gastro-intestinal effects: diarrhea, nausea, vomiting
    • Cutaneous reactions: rash, pruritus, urticaria
    • Hematologic reactions: eosinophilia, thrombocytopenia
    • Hepatic reactions: elevations of SGOT or SGPT, bilirubinemia
    • CNS reactions: nervousness, confusion, headache
    • Local Phlebitis: occurs rarely following intravenous administration
  • Pregnancy & Lactation:
    • Pregnancy: Safety not established; use only if absolutely indicated
    • Lactation: Exercise caution when administered to a lactating mother
  • Precautions & Warnings:
    • Anaphylactic shock may occur
    • Shadows suggesting sludge detected by sonograms of the gallbladder
    • Blood picture should be checked during prolonged treatment
  • Use in Special Populations: Not indicated for neonates if premature and newborn (up to 28 days of age)
  • Overdose Effects: No specific antidote; treatment should be symptomatic
  • Therapeutic Class: Third generation Cephalosporins
  • Storage Conditions: Store in a cool, dry place (below 30°C), away from light and moisture; Keep out of the reach of children

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