Ampil Plus 5 mg+50 mg (Tablet)

Unit Price: ৳ 6.00 (50's pack: ৳ 300.00)

Medicine Details

Indications

  • Essential hypertension
  • Angina pectoris
  • Post Ml
  • Refractory angina pectoris

Pharmacology

  • Fixed-dose combination of Amlodipine and Atenolol
  • Dihydropyridine calcium antagonist
  • Peripheral vasodilator
  • Cardioselective beta-blocker

Dosage & Administration

  • Recommended dosage of Amlodipine and Atenolol 5/25 mg tablet once daily
  • Dosage may be increased to 5/25 mg two tablets daily

Interaction

  • Atenolol reduces the clearance of disopyramide by 20%
  • Ampicillin at doses of 1 gm and above may reduce Atenolol levels
  • Beta-blockers may decrease tissue sensitivity to insulin and inhibit insulin secretion

Contraindications

  • Hypersensitivity to either component
  • Sinus bradycardia
  • Second and higher degrees of heart block
  • Cardiogenic shock
  • Hypotension
  • Congestive heart failure
  • Poor left ventricular function

Side Effects

  • Fatigue
  • Headache
  • Edema
  • Nausea
  • Drowsiness
  • Anxiety
  • Depression

Pregnancy & Lactation

  • Should be used during pregnancy only if the expected benefit outweighs the potential fetal risk
  • Should not be used by nursing mothers

Precautions & Warnings

  • Caution in patients with airway obstruction
  • Can be used in patients with renal impairment
  • Caution in patients with severe liver damage
  • Patients should be warned against stopping the drug suddenly

Overdose Effects

  • Hypotension
  • Congestive cardiac failure
  • Unabsorbed drugs may be removed by gastric lavage or administration of activated charcoal

Therapeutic Class

  • Combined antihypertensive preparations

Storage Conditions

  • Keep below 30°C temperature
  • Away from light & moisture
  • Keep out of the reach of children

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