Ampil Plus 5 mg+50 mg (Tablet)
Unit Price: ৳ 6.00 (50's pack: ৳ 300.00)
Medicine Details
Category | Details |
---|---|
Generic | Amlodipine besilate atenolol |
Company | The white horse pharmaceuticals ltd |
Indications
- Essential hypertension
- Angina pectoris
- Post Ml
- Refractory angina pectoris
Pharmacology
- Fixed-dose combination of Amlodipine and Atenolol
- Dihydropyridine calcium antagonist
- Peripheral vasodilator
- Cardioselective beta-blocker
Dosage & Administration
- Recommended dosage of Amlodipine and Atenolol 5/25 mg tablet once daily
- Dosage may be increased to 5/25 mg two tablets daily
Interaction
- Atenolol reduces the clearance of disopyramide by 20%
- Ampicillin at doses of 1 gm and above may reduce Atenolol levels
- Beta-blockers may decrease tissue sensitivity to insulin and inhibit insulin secretion
Contraindications
- Hypersensitivity to either component
- Sinus bradycardia
- Second and higher degrees of heart block
- Cardiogenic shock
- Hypotension
- Congestive heart failure
- Poor left ventricular function
Side Effects
- Fatigue
- Headache
- Edema
- Nausea
- Drowsiness
- Anxiety
- Depression
Pregnancy & Lactation
- Should be used during pregnancy only if the expected benefit outweighs the potential fetal risk
- Should not be used by nursing mothers
Precautions & Warnings
- Caution in patients with airway obstruction
- Can be used in patients with renal impairment
- Caution in patients with severe liver damage
- Patients should be warned against stopping the drug suddenly
Overdose Effects
- Hypotension
- Congestive cardiac failure
- Unabsorbed drugs may be removed by gastric lavage or administration of activated charcoal
Therapeutic Class
- Combined antihypertensive preparations
Storage Conditions
- Keep below 30°C temperature
- Away from light & moisture
- Keep out of the reach of children
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