Oryx 250 mg/vial (IV Injection)

250 mg vial: ৳ 100.00

Medicine Details

Category Details
Generic Ceftriaxone sodium
Company Rangs pharmaceuticals ltd
Also available as
Oryx 250 mg injection Oryx 500 mg injection Oryx 1 gm injection Oryx 500 mg injection Oryx 1 gm injection Oryx 2 gm injection

Indications

  • Lower respiratory tract infections
  • Acute Bacterial Otitis Media
  • Skin and skin structure infections
  • Urinary tract infections
  • Gonorrhea
  • Bacterial Septicemia
  • Bone and joint infections
  • Meningitis
  • Prevention of postoperative infections
  • Perioperative prophylaxis of infections associated with surgery

Pharmacology

  • Broad-spectrum antibiotic
  • Bactericidal activity
  • Potent against Gram-positive and Gram-negative organisms
  • Interferes with bacterial cell wall synthesis
  • Stable in the presence of beta lactamases
  • Long plasma elimination half-life (6 to 9 hours)
  • Not metabolized in the body
  • Highly protein bound (95%)

Dosage

  • Usual dose for adults: 1 to 2 gm by IV or IM once a day
  • Maximum adult dose: 4 gm/day
  • Usual dose for infants and children: 50 to 75 mg/kg by IV or IM once a day
  • Maximum pediatric dose: 4 gm/day
  • Duration of therapy: 4 to 14 days

Administration

  • Intramuscular or intravenous administration
  • Injection preparation for IM/IV injections
  • Administered over 2-4 minutes
  • Tubing infusion over 30 minutes
  • Patient tolerance test recommended

Interaction

No drug interactions reported

Contraindications

Hypersensitivity to cephalosporin antibiotics

Side Effects

  • Gastro-intestinal effects
  • Cutaneous reactions
  • Hematologic reactions
  • Hepatic reactions
  • CNS reactions
  • Local phlebitis

Pregnancy & Lactation

  • Safety not established in human pregnancy
  • Caution during lactation

Precautions & Warnings

  • Risk of anaphylactic shock
  • Possible gallbladder sludge
  • Blood picture should be checked during prolonged treatment

Use in Special Populations

Not for premature and newborn neonates

Overdose Effects

No specific antidote; symptomatic treatment

Therapeutic Class

Third generation Cephalosporins

Storage Conditions

Store vials below 30°C, away from light & moisture

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