Parcef 500 mg/vial (IM Injection)

500 mg vial: ৳ 110.00

Medicine Details

Category Details
Generic Ceftriaxone sodium
Company Jayson pharmaceuticals ltd
Also available as
Parcef 250 mg injection Parcef 1 gm injection Parcef 250 mg injection Parcef 500 mg injection Parcef 1 gm injection Parcef 2 gm injection

Indications

  • Lower respiratory tract infections
  • Acute Bacterial Otitis Media
  • Skin and skin structure infections
  • Urinary tract infections
  • Gonorrhea
  • Bacterial Septicemia
  • Bone and joint infections
  • Meningitis
  • Prevention of postoperative infections
  • Perioperative prophylaxis of infections associated with surgery

Pharmacology

Ceftriaxone is a 3rd generation broad-spectrum parenteral cephalosporin antibiotic with potent bactericidal activity against a wide range of Gram-positive and Gram-negative organisms. It kills bacteria by interfering with the synthesis of the bacterial cell wall.

Dosage

  • Adult:
    • 1 to 2 gm by intravenous or intramuscular administration once a day (or in equally divided doses twice a day)
    • Maximum dose: 4 gm/day
  • Infants and Children (01 month or older):
    • 50 to 75 mg/kg intravenous or intramuscular administration once a day (or in equally divided doses twice a day)
    • Maximum dose: 2 gm/day
    • Duration of therapy: 4 to 14 days

Administration

  • Preparation of Solutions for Intramuscular / Intravenous Injections
  • Intramuscular Injection: 250 mg or 500 mg Ceftriaxone should be dissolved in Lidocaine HCI 1% injection
  • Intravenous Injection: 250 mg or 500 mg Ceftriaxone should be dissolved in Water for injection
  • The injection should be administered over 2-4 minutes

Interaction

No drug interactions have been reported.

Contraindications

Ceftriaxone should not be given to patients with a history of hypersensitivity to cephalosporin antibiotics.

Side Effects

  • Diarrhea
  • Nausea and vomiting
  • Rash
  • Pruritus
  • Urticaria
  • Thrombocytopenia
  • Elevations of SGOT or SGPT
  • Local phlebitis following intravenous administration

Pregnancy & Lactation

Safety in human pregnancy has not been established. Low concentrations are excreted in human milk.

Precautions & Warnings

  • Anaphylactic shock may occur
  • Shadows suggesting sludge in the gallbladder detected in rare cases
  • Blood picture should be checked during prolonged treatment

Use in Special Populations

Must not be given to neonates if premature and newborn (up to 28 days of age).

Overdose Effects

No specific antidote. Treatment of overdosage should be symptomatic.

Therapeutic Class

Third generation Cephalosporins

Storage Conditions

Store in a cool, dry place (below 30°C), away from light & moisture. Keep out of the reach of children.

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