Parcef 500 mg/vial (IV Injection)
500 mg vial: ৳ 120.36
Medicine Details
| Category | Details |
|---|---|
| Generic | Ceftriaxone sodium |
| Company | Jayson pharmaceuticals ltd |
| Also available as |
Title
- Parcef
Categories
- Medicine
- Antibiotic
- Cephalosporin
Description
- Broad-spectrum antibiotic for major infections
- Third generation cephalosporin
- Intravenous and intramuscular administration
Indications
- Lower respiratory tract infections
- Acute Bacterial Otitis Media
- Skin and skin structure infections
- Urinary tract infections
- Gonorrhea
- Bacterial Septicemia
- Bone and joint infections
- Meningitis
- Prevention of postoperative infections
- Perioperative prophylaxis of infections associated with surgery
Pharmacology
- Potent bactericidal activity
- Works by interfering with bacterial cell wall synthesis
- High stability in presence of beta lactamases
- Long plasma elimination half-life of 6-9 hours
- Not metabolized in the body
- Excreted mainly in urine and bile
Dosage
- Adult dose: 1-2 gm once a day intravenously or intramuscularly
- Maximum daily dose: 4 gm
- Pediatric dose: 50-75 mg/kg once a day
- Duration of therapy: 4-14 days
Administration
- Preparation for intramuscular and intravenous injections
- Injected over 2-4 minutes or infused over 30 minutes
- Freshly reconstituted solution recommended
- Tolerance test advised before starting treatment
Interaction
- No reported drug interactions
Contraindications
- Hypersensitivity to cephalosporin antibiotics
Side Effects
- Well tolerated with few side effects
- Gastrointestinal effects, cutaneous reactions, hematologic reactions, hepatic reactions, CNS reactions, local phlebitis reported
Pregnancy & Lactation
- Safety not established in human pregnancy
- Cautious use during lactation due to excretion in human milk
Precautions & Warnings
- Risk of anaphylactic shock
- Monitoring gallbladder for sludge formation
- Regular blood picture checks during prolonged treatment
Use in Special Populations
- Avoid in premature and newborn neonates up to 28 days old
Overdose Effects
- No specific antidote, symptomatic treatment recommended
Therapeutic Class
- Third generation Cephalosporins
Storage Conditions
- Store vial below 30°C in a cool, dry place away from light and moisture
- Keep out of reach of children