Parcef 1 gm/vial (IV Injection)
1 gm vial: ৳ 175.00
Medicine Details
Category | Details |
---|---|
Generic | Ceftriaxone sodium |
Company | Jayson pharmaceuticals ltd |
Also available as |
Indications
- Lower respiratory tract infections
- Acute Bacterial Otitis Media
- Skin and skin structure infections
- Urinary tract infections
- Gonorrhea
- Bacterial Septicemia
- Bone and joint infections
- Meningitis
- Prevention of postoperative infections
- Perioperative prophylaxis of infections associated with surgery
Pharmacology
- Broad-spectrum parenteral cephalosporin antibiotic
- Potent bactericidal activity against a wide range of Gram-positive and Gram-negative organisms
- Interferes with the synthesis of the bacterial cell wall
- High stability in the presence of beta lactamases
- Relatively long plasma elimination half-life of about 6 to 9 hours
- Not metabolized in the body
Dosage
- Usual dose for adults: 1 to 2 gm by intravenous or intramuscular administration once a day (or in equally divided doses twice a day)
- Maximum dose for adults: 4 gm/day
- Usual dose for infants and children (01 month or older): 50 to 75 mg/kg intravenous or intramuscular administration once a day (or in equally divided doses twice a day)
- Maximum dose for infants and children: 2 gm/day
Administration
- Intramuscular injection preparation
- Intravenous injection preparation
- Patient tolerance test by administration of a test dose
- Freshly reconstituted solution recommended
- Injection should be administered over 2-4 minutes (for both intramuscular and intravenous injection)
Interaction
- No reported drug interactions
Contraindications
- Hypersensitivity to cephalosporin antibiotics
Side Effects
- Gastro-intestinal effects including diarrhea, nausea and vomiting, stomatitis and glossitis
- Cutaneous reactions including rash, pruritus, urticaria, edema, and erythema multiforme
- Hematologic reactions including eosinophilia, thrombocytopenia, leucopenia, anemia, and neutropenia
- Hepatic reactions including elevations of SGOT or SGPT, bilirubinemia
- CNS reactions including nervousness, confusion, sleep disturbances, headache, hyperactivity, convulsion, hypertonia, and dizziness
- Local phlebitis
Pregnancy & Lactation
- Safety in human pregnancy not established
- Caution should be exercised when administered to a lactating mother
Precautions & Warnings
- Anaphylactic shock possibility
- Shadows suggesting sludge have been detected by sonograms of the gallbladder
- Blood picture should be checked at regular intervals during prolonged treatment
Use in Special Populations
- Must not be given to neonates if premature and newborn (up to 28 days of age)
Overdose Effects
- No specific antidote
- Treatment should be symptomatic
Therapeutic Class
- Third generation Cephalosporins
Storage Conditions
- Vial store in a cool, dry place (below 30°C)
- Away from light & moisture
- Keep out of the reach of children
Related Brands
- Parcef 500 mg/vial (IV Injection) - jayson-pharmaceuticals-ltd
- Parcef 250 mg/vial (IV Injection) - jayson-pharmaceuticals-ltd
- Parcef 1 gm/vial (IM Injection) - jayson-pharmaceuticals-ltd
- Parcef 500 mg/vial (IM Injection) - jayson-pharmaceuticals-ltd
- Parcef 250 mg/vial (IM Injection) - jayson-pharmaceuticals-ltd