Perix 250 mg/vial (IM Injection)

250 mg vial: ৳ 90.00

Medicine Details

Category Details
Generic Ceftriaxone sodium
Company Monicopharma ltd
Also available as
Perix 500 mg injection Perix 1 gm injection Perix 250 mg injection Perix 500 mg injection Perix 1 gm injection Perix 2 gm injection

Indications

  • Lower respiratory tract infections
  • Acute Bacterial Otitis Media
  • Skin and skin structure infections
  • Urinary tract infections
  • Gonorrhea
  • Bacterial Septicemia
  • Bone and joint infections
  • Meningitis
  • Prevention of postoperative infections
  • Perioperative prophylaxis of infections associated with surgery

Pharmacology

  • Broad-spectrum antibiotic
  • Potent bactericidal activity
  • Interferes with bacterial cell wall synthesis
  • High stability in the presence of beta lactamases
  • Long plasma elimination half-life
  • Not metabolized in the body
  • Highly protein bound (95%)

Dosage

  • Usual dose for adults: 1 to 2 gm by intravenous or intramuscular administration once a day
  • Maximum adult dose: 4 gm/day
  • Usual dose for infants and children: 50 to 75 mg/kg intravenous or intramuscular administration once a day
  • Maximum dose for children: 2 gm/day
  • Duration of therapy: 4 to 14 days

Administration

  • Preparation of Solutions for Intramuscular / Intravenous Injections
  • Administration over 2-4 minutes
  • Patient tolerance test before starting treatment
  • Maintains potency for at least 6 hours at room temperature or 24 hours at 5°C

Interaction

  • No reported drug interactions

Contraindications

  • Contraindicated in patients with hypersensitivity to cephalosporin antibiotics

Side Effects

  • Gastro-intestinal effects including diarrhea, nausea, vomiting
  • Cutaneous reactions including rash, pruritus, urticaria
  • Hematologic reactions including eosinophilia, thrombocytopenia, leucopenia
  • Hepatic reactions including elevated liver enzymes
  • CNS reactions including nervousness, confusion, headache
  • Local phlebitis following intravenous administration

Pregnancy & Lactation

  • Not established for safety in human pregnancy
  • Cautious use in lactating mothers

Precautions & Warnings

  • Risk of anaphylactic shock
  • Sonogram shadows in the gallbladder
  • Regular blood picture check during prolonged treatment

Use in Special Populations

  • Not recommended for neonates if premature or newborn (up to 28 days of age)

Overdose Effects

  • No specific antidote
  • Symptomatic treatment

Therapeutic Class

  • Third generation Cephalosporins

Storage Conditions

  • Store in a cool, dry place (below 30°C)
  • Protect from light and moisture
  • Keep out of the reach of children

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