Perix 500 mg/vial (IM Injection)

500 mg vial: ৳ 120.00

Medicine Details

Category Details
Generic Ceftriaxone sodium
Company Monicopharma ltd
Also available as
Perix 250 mg injection Perix 1 gm injection Perix 250 mg injection Perix 500 mg injection Perix 1 gm injection Perix 2 gm injection

Indications

  • Lower respiratory tract infections
  • Acute Bacterial Otitis Media
  • Skin and skin structure infections
  • Urinary tract infections
  • Gonorrhea
  • Bacterial Septicemia
  • Bone and joint infections
  • Meningitis
  • Prevention of postoperative infections
  • Perioperative prophylaxis of infections associated with surgery

Pharmacology

  • 3rd generation broad-spectrum parenteral cephalosporin antibiotic
  • Potent bactericidal activity against a wide range of Gram-positive and Gram-negative organisms
  • Long plasma elimination half-life of 6 to 9 hours
  • Not metabolized in the body
  • Highly protein bound (95%)

Dosage

  • Usual adult dose of 1 to 2 gm by intravenous or intramuscular administration once a day
  • Special dosage for uncomplicated gonococcal infections and surgical prophylaxis
  • Usual infant and children's dose of 50 to 75 mg/kg intravenous or intramuscular administration once a day
  • Duration of therapy is 4 to 14 days

Administration

  • Preparation of solutions for intramuscular / intravenous injections with specific water and Lidocaine HCI concentrations
  • Injection should be administered over 2-4 minutes for intramuscular or intravenous administration or by tubing infusion over a period of 30 minutes
  • Freshly reconstituted solution is recommended

Interaction

  • No reported drug interactions

Contraindications

  • Not to be given to patients with a history of hypersensitivity to cephalosporin antibiotics

Side Effects

  • Gastro-intestinal effects
  • Cutaneous reactions
  • Hematologic reactions
  • Hepatic reactions
  • CNS reactions
  • Local phlebitis following intravenous administration

Pregnancy & Lactation

  • Safety in human pregnancy not established
  • Low concentrations excreted in human milk
  • Caution should be exercised when administered to a lactating mother

Precautions & Warnings

  • Anaphylactic shock precautions
  • Gallbladder issues
  • Blood picture should be checked at regular intervals during prolonged treatment

Use in Special Populations

  • Must not be given to neonates if premature and newborn (up to 28 days of age)

Overdose Effects

  • No specific antidote. Treatment should be symptomatic

Therapeutic Class

  • Third generation Cephalosporins

Storage Conditions

  • Vial store in a cool, dry place (below 30°C), away from light & moisture. Keep out of the reach of children

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