Amtinol Plus 5 mg+50 mg (Tablet)
Unit Price: ৳ 7.50 (5 x 10: ৳ 375.00)
Strip Price: ৳ 75.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Amlodipine besilate atenolol |
| Company | Euro pharma ltd |
Indications
- Essential hypertension
- Angina pectoris and hypertension
- Post myocardial infarction
- Refractory angina pectoris
Pharmacology
- Fixed-dose combination of Amlodipine and Atenolol
- Inhibits transmembrane influx of calcium ions
- Acts as a peripheral vasodilator
- Selective beta-blocker
- Reduces blood pressure
- Lowers cardiac demand and afterload
Dosage & Administration
- Recommended dosage: 5/25 mg tablet once daily
- Dosage may be increased as advised by physicians
- Individualized dosage
Interaction
- Disopyramide: Reduces clearance, additive negative inotropic effects
- Ampicillin: May reduce Atenolol levels
- Oral antidiabetics and insulin: Beta-blockers may decrease tissue sensitivity to insulin
Contraindications
- Hypersensitivity to either component
- Sinus bradycardia
- Second and higher degrees of heart block
- Cardiogenic shock
- Hypotension
- Congestive heart failure
- Poor left ventricular function
Side Effects
- Overall well tolerated
- Side effects include fatigue, headache, edema, nausea, drowsiness, anxiety, depression
Pregnancy & Lactation
- Use during pregnancy if expected benefit outweighs potential fetal risk
- Not recommended for nursing mothers
Precautions & Warnings
- Bronchospasm: Use with caution in patients with airway obstruction
- Renal impairment: Can be used with caution
- Hepatic impairment: Caution necessary in severe liver damage
- Drug withdrawal: Discontinuation should be gradual and under observation
Overdose Effects
- Hypotension
- Congestive cardiac failure
- Unabsorbed drugs may be removed by gastric lavage or activated charcoal
Therapeutic Class
- Combined antihypertensive preparations
Storage Conditions
Keep below 30°C, away from light & moisture, out of reach of children