Perix 2 gm/vial (IV Injection)
2 gm vial: ৳ 300.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Ceftriaxone sodium |
| Company | Monicopharma ltd |
| Also available as |
Indications
- Lower respiratory tract infections
- Acute Bacterial Otitis Media
- Skin and skin structure infections
- Urinary tract infections
- Gonorrhea
- Bacterial Septicemia
- Bone and joint infections
- Meningitis
- Prevention of postoperative infections
- Perioperative prophylaxis of infections associated with surgery
Pharmacology
- Broad-spectrum parenteral cephalosporin antibiotic
- Bactericidal activity against a wide range of Gram-positive and Gram-negative organisms
- Interference with the synthesis of the bacterial cell wall
- Long plasma elimination half-life of about 6 to 9 hours
- Not metabolized in the body
- Highly protein bound (95%)
Dosage
- Adult dose of 1 to 2 gm by intravenous or intramuscular administration once a day
- Maximum adult dose of 4 gm/day
- Infants and Children dose of 50 to 75 mg/kg intravenous or intramuscular administration once a day
- Maximum infants and children dose of 2 gm/day
- Duration of therapy: 4 to 14 days
Administration
- Preparation of Solutions for Intramuscular / Intravenous Injections
- Intramuscular injection using Lidocaine HCI 1% injection
- Intravenous injection using Water for injection
- Injection administered over 2-4 minutes
Interaction
- No reported drug interactions
Contraindications
- Hypersensitivity to cephalosporin antibiotics
Side Effects
- Gastro-intestinal effects including diarrhea, nausea, and vomiting
- Cutaneous reactions including rash, pruritus, and urticaria
- Hematologic reactions including eosinophilia, thrombocytopenia, and anemia
- Hepatic reactions including elevations of SGOT or SGPT
- CNS reactions including nervousness, confusion, and headache
- Local phlebitis following intravenous administration
Pregnancy & Lactation
- Not established safety in human pregnancy
- Low concentrations excreted in human milk
Precautions & Warnings
- Risk of anaphylactic shock
- Possible gallbladder complications
- Blood picture should be checked during prolonged treatment
Use in Special Populations
- Not to be given to neonates if premature and newborn (up to 28 days of age)
Overdose Effects
- No specific antidote
- Symptomatic treatment
Therapeutic Class
- Third generation Cephalosporins
Storage Conditions
- Store in a cool, dry place (below 30°C)
- Away from light & moisture
- Keep out of the reach of children