Powercef 1 gm/vial (IV Injection)

1 gm vial: ৳ 187.00

Medicine Details

Indications

  • Lower respiratory tract infections
  • Acute Bacterial Otitis Media
  • Skin and skin structure infections
  • Urinary tract infections
  • Gonorrhea
  • Bacterial Septicemia
  • Bone and joint infections
  • Meningitis
  • Prevention of postoperative infections
  • Perioperative prophylaxis of infections associated with surgery

Pharmacology

  • Broad-spectrum antibiotic
  • Bactericidal activity
  • Gram-positive and Gram-negative organisms
  • Interferes with bacterial cell wall synthesis
  • Long plasma elimination half-life
  • Stability in the presence of beta lactamases
  • Not metabolized in the body
  • Excretion in urine and feces
  • Highly protein bound

Dosage

  • Adult dosage: 1 to 2 gm by intravenous or intramuscular administration once a day
  • Maximum adult dose: 4 gm/day
  • Pediatric dosage: 50 to 75 mg/kg intravenous or intramuscular administration once a day
  • Duration of therapy: 4 to 14 days

Administration

  • Intramuscular injection preparation with Lidocaine HCI
  • Intravenous injection preparation with Water for injection
  • Injection administration over 2-4 minutes
  • Patient tolerance test before administration

Interaction

  • No reported drug interactions

Contraindications

  • Hypersensitivity to cephalosporin antibiotics

Side Effects

  • Gastrointestinal effects
  • Cutaneous reactions
  • Hematologic reactions
  • Hepatic reactions
  • CNS reactions
  • Local phlebitis

Pregnancy & Lactation

  • Unestablished safety in human pregnancy
  • Low concentrations excreted in human milk
  • Caution in lactating mothers

Precautions & Warnings

  • Potential for anaphylactic shock
  • Gallbladder sonogram shadows
  • Blood picture monitoring during prolonged treatment

Use in Special Populations

  • Avoid use in premature and newborn neonates (up to 28 days of age)

Overdose Effects

  • No specific antidote
  • Symptomatic treatment recommended

Therapeutic Class

  • Third generation Cephalosporins

Storage Conditions

  • Store below 30° C
  • Keep away from light and moisture
  • Keep out of reach of children

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