Rit 1 gm/vial (IM Injection)

1 gm vial: ৳ 190.58

Medicine Details

Indications

  • Lower respiratory tract infections
  • Acute Bacterial Otitis Media
  • Skin and skin structure infections
  • Urinary tract infections
  • Gonorrhea
  • Bacterial Septicemia
  • Bone and joint infections
  • Meningitis
  • Prevention of postoperative infections
  • Perioperative prophylaxis of infections associated with surgery

Pharmacology

  • Broad-spectrum parenteral cephalosporin antibiotic
  • Bactericidal activity against a wide range of Gram-positive and Gram-negative organisms
  • Interferes with the synthesis of the bacterial cell wall
  • Long plasma elimination half-life of about 6 to 9 hours

Dosage

  • Usual dose of 1 to 2 gm by intravenous or intramuscular administration once a day
  • Dosage based on specific infections and age groups
  • Adult and pediatric dosages specified
  • Duration of therapy typically 4 to 14 days

Administration

  • Instructions on preparation of solutions for intramuscular/intravenous injections
  • Guidelines for administration via intramuscular or intravenous injection or tubing infusion
  • Recommendation for patient tolerance test before treatment

Interaction

  • No reported drug interactions

Contraindications

  • Not to be given to patients with a history of hypersensitivity to cephalosporin antibiotics

Side Effects

  • Gastro-intestinal effects
  • Cutaneous reactions
  • Hematologic reactions
  • Hepatic reactions
  • CNS reactions
  • Rare occurrence of local phlebitis following intravenous administration

Pregnancy & Lactation

  • Safety in human pregnancy not established
  • Caution advised when administered to lactating mothers

Precautions & Warnings

  • Possibility of anaphylactic shock
  • Detection of gallbladder sludge under rare circumstances
  • Need for regular blood picture checks during prolonged treatment

Use in Special Populations

  • Avoid use in neonates if premature or newborn up to 28 days of age

Overdose Effects

  • No specific antidote
  • Symptomatic treatment recommended for overdosage

Therapeutic Class

  • Third generation Cephalosporins

Storage Conditions

  • Vial storage in a cool, dry place (below 30°C)
  • Protection from light and moisture
  • Keep out of the reach of children

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