Atepine 5 mg+50 mg (Tablet)
Unit Price: ৳ 4.50 (30's pack: ৳ 135.00)
Medicine Details
| Category | Details |
|---|---|
| Generic | Amlodipine besilate atenolol |
| Company | Pharmadesh laboratories ltd |
| Also available as |
Indications
- Essential hypertension
- Angina pectoris & hypertension
- Post myocardial infarction
- Refractory angina pectoris
Pharmacology
- Dihydropyridine calcium antagonist
- Peripheral vasodilator
- Cardioselective beta-blocker
- Reduction in blood pressure
- Reduction in peripheral vascular resistance
- Reduction in myocardial oxygen demand
Dosage & Administration
- Recommended dosage: Amlodipine and Atenolol 5/25 mg tablet once daily
- Dosage may be increased as advised by physicians
- Individualized dosage
Interaction
- Disopyramide: Atenolol reduces clearance by 20%
- Ampicillin: may reduce Atenolol levels
- Oral antidiabetics and insulin: Beta-blockers may decrease tissue sensitivity to insulin
Contraindications
- Hypersensitivity to either component
- Sinus bradycardia
- Second and higher degrees of heart block
- Cardiogenic shock
- Hypotension
- Congestive heart failure
- Poor left ventricular function
Side Effects
- Fatigue
- Headache
- Edema
- Nausea
- Drowsiness
- Anxiety
- Depression
Pregnancy & Lactation
- Use during pregnancy only if benefit outweighs potential fetal risk
- Not recommended for nursing mothers
- Stop breast-feeding if use is considered necessary
Precautions & Warnings
- Bronchospasm caution
- Use with caution in patients with airway obstruction
- Can be used in patients with renal impairment
- Caution in severe liver damage
- Warn against sudden drug withdrawal
Overdose Effects
- Hypotension
- Congestive cardiac failure
- Unabsorbed drugs removal by gastric lavage or activated charcoal
- Symptomatic treatment is suggested
Therapeutic Class
- Combined antihypertensive preparations
Storage Conditions
- Keep below 30°C temperature
- Away from light & moisture
- Keep out of the reach of children