Rofecin 2 gm/vial (IV Injection)

2 gm vial: ৳ 682.05

Medicine Details

Category Details
Generic Ceftriaxone sodium
Company Radiant pharmaceuticals ltd
Also available as
Rofecin 500 mg injection Rofecin 1 gm injection Rofecin 500 mg injection Rofecin 1 gm injection

Title and Categories

  • Rofecin
  • Third generation Cephalosporins

Indications

  • Lower respiratory tract infections
  • Acute Bacterial Otitis Media
  • Skin and skin structure infections
  • Urinary tract infections
  • Gonorrhea
  • Bacterial Septicemia
  • Bone and joint infections
  • Meningitis
  • Prevention of postoperative infections
  • Perioperative prophylaxis of infections associated with surgery

Pharmacology

  • Broad-spectrum parenteral cephalosporin antibiotic
  • Bactericidal activity
  • Interferes with bacterial cell wall synthesis
  • Stability in the presence of beta lactamases
  • Long plasma elimination half-life
  • High degree of protein binding

Dosage

  • Adult dosage 1-2 gm by intravenous or intramuscular administration once a day
  • Infant and Children dosage 50-75 mg/kg intravenous or intramuscular administration once a day
  • Dosage for various infections
  • Maximum daily dose for different indications

Administration

  • Preparation of solutions for intramuscular and intravenous injections
  • Recommended injection administration time and concentration
  • Test dose recommendation
  • Recommendation for freshly reconstituted solution usage and potency maintenance

Interaction

  • No reported drug interactions

Contraindications

  • Should not be given to patients with history of hypersensitivity to cephalosporin antibiotics

Side Effects

  • Gastro-intestinal effects
  • Cutaneous reactions
  • Hematologic reactions
  • Hepatic reactions
  • CNS reactions
  • Local phlebitis
  • Minimization of local phlebitis
  • Rare side effects
  • Well-tolerated nature

Pregnancy & Lactation

  • Safety not established in human pregnancy
  • Caution in lactating mothers due to excretion in human milk

Precautions & Warnings

  • Anaphylactic shock
  • Sonogram findings related to gallbladder
  • Regular blood picture checks during prolonged treatment

Use in Special Populations

  • Avoid in neonates, premature and newborn infants up to 28 days old

Overdose Effects

  • No specific antidote
  • Symptomatic treatment

Storage Conditions

  • Cool, dry place below 30°C
  • Protection from light and moisture
  • Keep out of reach of children

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