Topcef 1 gm/vial (IM Injection)
1 gm vial: ৳ 190.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Ceftriaxone sodium |
| Company | Navana pharmaceuticals ltd |
| Also available as |
Indications
- Lower respiratory tract infections
- Acute Bacterial Otitis Media
- Skin and skin structure infections
- Urinary tract infections
- Gonorrhea
- Bacterial Septicemia
- Bone and joint infections
- Meningitis
- Prevention of postoperative infections
- Perioperative prophylaxis of infections associated with surgery
Pharmacology
- Broad-spectrum antibiotic
- Bactericidal activity
- Gram-positive and Gram-negative organisms
- Interference with bacterial cell wall synthesis
- Stability in the presence of beta lactamases
- Long plasma elimination half-life
- Not metabolized in the body
- Excretion in urine and bile
- Highly protein bound
Dosage
- Adult dose: 1 to 2 gm by intravenous or intramuscular administration once a day
- Maximum adult dose: 4 gm/day
- Infants and Children dose: 50 to 75 mg/kg intravenous or intramuscular administration once a day
- Maximum pediatric dose: 2 gm/day
- Duration of therapy: 4 to 14 days
Administration
- Preparation of Solutions for Intramuscular / Intravenous Injections
- Injection over 2-4 minutes
- Patient tolerance test
- Storage recommendation for reconstituted solution
Interaction
- No reported drug interactions
Contraindications
- Hypersensitivity to cephalosporin antibiotics
Side Effects
- Gastro-intestinal effects
- Cutaneous reactions
- Hematologic reactions
- Hepatic reactions
- CNS reactions
- Local phlebitis following intravenous administration
Pregnancy & Lactation
- Safety not established in human pregnancy
- Caution in lactating mothers
Precautions & Warnings
- Potential for anaphylactic shock
- Sonogram findings in gallbladder
- Regular blood picture checks during prolonged treatment
Use in Special Populations
- Avoid use in premature and newborn neonates
Overdose Effects
- No specific antidote
- Symptomatic treatment
Therapeutic Class
- Third generation Cephalosporins
Storage Conditions
- Store in a cool, dry place (below 30° C)
- Away from light & moisture
- Keep out of the reach of children