Trax 500 mg/vial (IM Injection)

500 mg vial: ৳ 120.00

Medicine Details

Category Details
Generic Ceftriaxone sodium
Company Medimet pharmaceuticals ltd
Also available as
Trax 250 mg injection Trax 1 gm injection Trax 250 mg injection Trax 500 mg injection Trax 1 gm injection

Indications

  • Lower respiratory tract infections
  • Acute Bacterial Otitis Media
  • Skin and skin structure infections
  • Urinary tract infections
  • Gonorrhea
  • Bacterial Septicemia
  • Bone and joint infections
  • Meningitis
  • Prevention of postoperative infections
  • Perioperative prophylaxis of infections associated with surgery

Pharmacology

  • Broad-spectrum parenteral cephalosporin antibiotic
  • Potent bactericidal activity
  • Interferes with bacterial cell wall synthesis
  • Long plasma elimination half-life of 6 to 9 hours
  • High degree of stability in the presence of beta lactamases
  • Not metabolized in the body
  • About 40-65% of a dose excreted unchanged in the urine
  • Highly protein bound (95%)

Dosage

  • Usual adult dose of 1 to 2 gm by intravenous or intramuscular administration once a day
  • Maximum adult dose of 4 gm/day
  • 250 mg IM dose for uncomplicated gonococcal infections
  • Infant and children dosage of 50 to 75 mg/kg intravenous or intramuscular administration
  • Duration of therapy of 4 to 14 days

Administration

  • Preparation of solutions for intramuscular / intravenous injections
  • Administration over 2-4 minutes for intramuscular or intravenous injection
  • Slow injections over 2-4 minutes to minimize local phlebitis

Interaction

  • No reported drug interactions

Contraindications

  • Not to be given to patients with a history of hypersensitivity to cephalosporin antibiotics

Side Effects

  • Gastro-intestinal effects including diarrhea, nausea, vomiting
  • Cutaneous reactions including rash, pruritus, urticaria
  • Hematologic reactions including eosinophilia, thrombocytopenia, leucopenia
  • Hepatic reactions including elevations of SGOT or SGPT, bilirubinemia
  • CNS reactions including nervousness, confusion, sleep disturbances

Pregnancy & Lactation

  • Safety in human pregnancy not established
  • Caution advised when administered to lactating mothers

Precautions & Warnings

  • Anaphylactic shock precaution
  • Sonogram detection of gallbladder sludge
  • Regular blood picture checks during prolonged treatment

Use in Special Populations

  • Must not be given to neonates if premature and newborn (up to 28 days of age)

Overdose Effects

  • No specific antidote
  • Symptomatic treatment advised

Therapeutic Class

  • Third generation Cephalosporins

Storage Conditions

  • Store in a cool, dry place below 30°C
  • Store away from light and moisture
  • Keep out of the reach of children

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