Trax 1 gm/vial (IM Injection)

1 gm vial: ৳ 160.00

Medicine Details

Category Details
Generic Ceftriaxone sodium
Company Medimet pharmaceuticals ltd
Also available as
Trax 250 mg injection Trax 500 mg injection Trax 250 mg injection Trax 500 mg injection Trax 1 gm injection

Indications

  • Lower respiratory tract infections
  • Acute Bacterial Otitis Media
  • Skin and skin structure infections
  • Urinary tract infections
  • Gonorrhea
  • Bacterial Septicemia
  • Bone and joint infections
  • Meningitis
  • Prevention of postoperative infections
  • Perioperative prophylaxis of infections associated with surgery

Pharmacology

  • Broad-spectrum parenteral cephalosporin antibiotic
  • Bactericidal activity against wide range of Gram-positive and Gram-negative organisms
  • Interferes with synthesis of bacterial cell wall
  • High stability in presence of beta lactamases
  • Relatively long plasma elimination half-life of 6 to 9 hours
  • Not metabolized in the body
  • Highly protein bound (95%)

Dosage

  • Usual adult dose of 1 to 2 gm intravenously or intramuscularly once a day
  • Maximum adult dose of 4 gm/day
  • 250 mg intramuscular dose for uncomplicated gonococcal infections
  • Infant and child doses of 50 to 75 mg/kg intravenously or intramuscularly once a day
  • Maximum infant and child dose of 2 gm/day
  • Duration of therapy usually 4 to 14 days

Administration

  • Preparation of solutions for intramuscular / intravenous injections
  • Intramuscular injection preparation in Lidocaine HCI 1% injection
  • Intravenous injection preparation in Water for injection
  • Administration over 2-4 minutes for intramuscular or intravenous injection or by tubing infusion over 30 minutes
  • Patient tolerance test recommended before treatment
  • Solution potency maintained for at least 6 hours at room temperature or 24 hours at 5°C

Interaction

  • No reported drug interactions

Contraindications

  • History of hypersensitivity to cephalosporin antibiotics

Side Effects

  • Gastro-intestinal effects including diarrhea, nausea, and vomiting
  • Cutaneous reactions including rash, pruritus, and urticaria
  • Hematologic reactions including eosinophilia and thrombocytopenia
  • Hepatic reactions including elevations of SGOT or SGPT
  • CNS reactions including nervousness, confusion, and sleep disturbances
  • Rare local phlebitis following intravenous administration

Pregnancy & Lactation

  • Safety in human pregnancy not established
  • Use in pregnancy only if absolutely indicated
  • Low concentrations excreted in human milk
  • Caution during lactation

Precautions & Warnings

  • Potential for anaphylactic shock
  • Rare cases of gallbladder sludge detected
  • Blood picture should be checked during prolonged treatment

Use in Special Populations

  • Not to be given to premature and newborn neonates

Overdose Effects

  • No specific antidote
  • Symptomatic treatment recommended

Therapeutic Class

  • Third generation Cephalosporins

Storage Conditions

  • Store in a cool, dry place below 30°C
  • Keep away from light and moisture
  • Keep out of the reach of children

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