Traxon 1 gm/vial (IM Injection)

1 gm vial: ৳ 210.00

Medicine Details

Category Details
Generic Ceftriaxone sodium
Company Opsonin pharma ltd
Also available as
Traxon 250 mg injection Traxon 500 mg injection Traxon 250 mg injection Traxon 500 mg injection Traxon 1 gm injection Traxon 2 gm injection

Indications

  • Lower respiratory tract infections
  • Acute Bacterial Otitis Media
  • Skin and skin structure infections
  • Urinary tract infections
  • Gonorrhea
  • Bacterial Septicemia
  • Bone and joint infections
  • Meningitis
  • Prevention of postoperative infections
  • Perioperative prophylaxis of infections associated with surgery

Pharmacology

  • Broad-spectrum parenteral cephalosporin antibiotic
  • Bactericidal activity against a wide range of Gram-positive and Gram-negative organisms
  • Interferes with the synthesis of the bacterial cell wall
  • High stability in the presence of beta lactamases
  • Relatively long plasma elimination half-life of about 6 to 9 hours
  • Not metabolized in the body
  • Highly protein bound (95%)

Dosage

  • Usual adult dose: 1 to 2 gm by intravenous or intramuscular administration once a day
  • Children's dose: 50 to 75 mg/kg intravenous or intramuscular administration once a day
  • Different doses for various infections and age groups
  • Duration of therapy: Continue for more than 2 days after signs and symptoms of infection have disappeared

Administration

  • Preparation of Solutions for Intramuscular / Intravenous Injections
  • Different dilution instructions for intramuscular and intravenous injections
  • Injection should be administered over 2-4 minutes or by tubing infusion over a period of 30 minutes

Interaction

  • No drug interactions reported

Contraindications

  • History of hypersensitivity to cephalosporin antibiotics

Side Effects

  • Gastro-intestinal effects including diarrhea, nausea, vomiting, stomatitis, and glossitis
  • Cutaneous reactions including rash, pruritus, urticaria, edema, and erythema multiforme
  • Hematologic reactions including eosinophilia, thrombocytopenia, leucopenia, anemia, and neutropenia
  • Hepatic reactions including elevations of SGOT or SGPT, bilirubinemia
  • CNS reactions including nervousness, confusion, sleep disturbances, headache, hyperactivity, convulsion, hypertonia, and dizziness
  • Local phlebitis occurs rarely following intravenous administration

Pregnancy & Lactation

  • Safety in human pregnancy not established
  • Caution should be exercised when administered to a lactating mother

Precautions & Warnings

  • Anaphylactic shock cannot be ruled out
  • Shadows suggesting sludge have been detected by sonograms of the gallbladder
  • Blood picture should be checked at regular intervals during prolonged treatment

Use in Special Populations

  • Must not be given to neonates if premature and newborn (up to 28 days of age)

Overdose Effects

  • No specific antidote
  • Treatment should be symptomatic

Therapeutic Class

  • Third generation Cephalosporins

Storage Conditions

  • Store in a cool, dry place (below 30° C)
  • Keep away from light and moisture
  • Keep out of the reach of children

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